Protein Alignment Pgcl and Ren

DIOPT Version :10

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_036774.4
• Gene: Ren / 24715
• RGDID: 3554
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 141/381 - (37%)
• Similarity: 210/381 - (55%)
• Gaps: 43/381 - (11%)

  Fly    28 RIPIQKSPNFKRSHKNIVAER------------DFVQQKYNRQYTANGYPMEHLSNYDNFQYYGN 80
            ||.::|.|    |.:.|:.||            :|:::.   .:|....|:. |:||.:.||||.
  Rat    31 RILLKKMP----SVREILEERGVDMTRISAEWGEFIKKS---SFTNVTSPVV-LTNYLDTQYYGE 87

  Fly    81 ISIGTPGQDFLVQFDTGSSNLWVPGSSC--ISTACQDHQVFYKNKSSTYVANGTAFSITYGTGSV 143
            |.||||.|.|.|.|||||:|||||.:.|  :.|||:.|.::..::||:|:.|||.|:|.||:|.|
  Rat    88 IGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENGTEFTIHYGSGKV 152

  Fly   144 SGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVTPTFQNMMQQGL 208
            .|:||.|.|...|: |.:|||||||......|:.|.|||:||||||:.|||||.|.|.:::.|.:
  Rat   153 KGFLSQDVVTVGGI-IVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRV 216

  Fly   209 VQSPVFS-FFLRDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTDYIKVGSTSI-- 270
            ::..||| ::.|::   ...|||::||||||..|.|:..||::.:|..|:.....:.||..::
  Rat   217 LKEEVFSVYYSRES---HLLGGEVVLGGSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLC 278

  Fly   271 STFAQAIADTGTSLIIAPQAQYDQISQLFNANSEG----LFECSST-SYPDLIININGVDFKIPA 330
            .....|:.|||||.|..|.:....|.|......:.    :..||.. :.||:...:.|..:.:..
  Rat   279 EEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSN 343

  Fly   331 KYYI----IEEEDFCSLAIQSIN-----QDFWIMGDVFLGRIYTEFDVGNQRLGFA 377
            ..|:    ...:|.|.||:|.::     ...|::|..|:.:.|||||..|.|:|||
  Rat   344 MDYVQKNPFRNDDLCILALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	Asp	76..379	CDD:394983	127/321 (40%)
Ren	NP_036774.4	A1_Propeptide	31..64	CDD:462326	9/36 (25%)
		renin_like	76..401	CDD:133154	130/328 (40%)