| Sequence 1: | NP_525030.1 | Gene: | Pgcl / 30984 | FlyBaseID: | FBgn0011822 | Length: | 407 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036236.1 | Gene: | BACE1 / 23621 | HGNCID: | 933 | Length: | 501 | Species: | Homo sapiens |
| Alignment Length: | 368 | Identity: | 87/368 - (23%) |
|---|---|---|---|
| Similarity: | 153/368 - (41%) | Gaps: | 79/368 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 73 DNFQ------YYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQD--HQVFYKNKSSTYVA 129
Fly 130 NGTAFSITYGTGSVSGYLSVDCVGF---AGLTIQSQTFGEVTTEQGTNFVD-AYFDGILGMGFPS 190
Fly 191 LA--VDGVTPTFQNMMQQGLVQSPVFS-------FFLRDNGSVTFYGGELILGGSDPSLYSGSLT 246
Fly 247 YVNVVQAAYWKFQTDYIKVGSTSIS------TFAQAIADTGTSLIIAPQAQYDQISQLFNANSEG 305
Fly 306 LFECSST-SYPD---------------------------LIININGVDFKI---PAKYY-----I 334
Fly 335 IEEEDFCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLGFA 377 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pgcl | NP_525030.1 | pepsin_retropepsin_like | 67..378 | CDD:299705 | 87/368 (24%) |
| Asp | 76..379 | CDD:278455 | 85/365 (23%) | ||
| BACE1 | NP_036236.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 39..58 | ||
| beta_secretase_like | 72..437 | CDD:133140 | 85/361 (24%) | ||
| Interaction with RTN3 | 479..501 | ||||
| DXXLL. /evidence=ECO:0000269|PubMed:15886016 | 496..500 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1339 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||