Protein Alignment Pgcl and Ren1

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_112469.1
• Gene: Ren1 / 19701
• MGIID: 97898
• Length: 402
• Species: Mus musculus
• Alignment Length: 381
• Identity: 141/381 - (37%)
• Similarity: 214/381 - (56%)
• Gaps: 35/381 - (9%)

  Fly    24 STLRRIPIQKSPNFKRSHKNIVAERDFVQQKYNRQY---------TANGYPMEHLSNYDNFQYYG 79
            :|..|||::|.|    |.:.|:.||.....:.:.::         |....|:. |:||.|.||||
Mouse    27 ATFERIPLKKMP----SVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVV-LTNYLNTQYYG 86

  Fly    80 NISIGTPGQDFLVQFDTGSSNLWVPGSSC--ISTACQDHQVFYKNKSSTYVANGTAFSITYGTGS 142
            .|.||||.|.|.|.|||||:|||||.:.|  :..||..|.::..:.||:|:.||:.|:|.||:|.
Mouse    87 EIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGR 151

  Fly   143 VSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVTPTFQNMMQQG 207
            |.|:||.|.|...|:|: :|||||||......|:.|.|||:||||||:.||.||||.|.:::.||
Mouse   152 VKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQG 215

  Fly   208 LVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTDYIKVGSTSI-- 270
            :::..|||.:.  |......|||::||||||..|.|:..||::.:...|:.....:.|||:::
Mouse   216 VLKEEVFSVYY--NRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLC 278

  Fly   271 STFAQAIADTGTSLIIAPQAQYDQISQLFNANSEGLFE----CSST-SYPDLIININGVDFKIPA 330
            ......:.|||:|.|.||.:....|.|...|..:.:.|    ||.. :.||:..::.|..:.:.:
Mouse   279 EEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSS 343

  Fly   331 KYYIIE----EEDFCSLAIQSIN-----QDFWIMGDVFLGRIYTEFDVGNQRLGFA 377
            ..|:::    .:..|:||:.:::     ...|::|..|:.:.|||||..|.|:|||
Mouse   344 TDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	129/329 (39%)
		Asp	76..379	CDD:278455	125/320 (39%)
Ren1	NP_112469.1	A1_Propeptide	29..54	CDD:285240	9/28 (32%)
		renin_like	76..401	CDD:133154	129/327 (39%)
		Asp	83..401	CDD:278455	125/320 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880