Protein Alignment Pgcl and asp-18

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_507653.2
• Gene: asp-18 / 191310
• WormBaseID: WBGene00013973
• Length: 392
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 133/410 - (32%)
• Similarity: 204/410 - (49%)
• Gaps: 62/410 - (15%)

  Fly    15 LIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAE---RDFVQQKYNRQYTANGYPMEHLSNYDNFQ 76
            |::||...::.:.::|...|.:|:   ..::.|   ..|:..:..:..|.:    :.|..:.:..
 Worm     4 LLLLVTTCSAAVFQVPTTTSGSFR---AKLIREGKYSSFLASRLQQLNTGS----QPLLGFSDDP 61

  Fly    77 YYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQD-------HQVFYKNKSSTYVANGTAF 134
            ..|||:||:|.|...|..||.|:||||.||:|.|..|.|       |: |...||:::|.:...|
 Worm    62 CIGNITIGSPPQSAFVFMDTTSANLWVMGSACTSVNCNDPLLGIIKHK-FNTTKSTSFVKSNRKF 125

  Fly   135 SITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYF-----DGILGMGFPSLAVD 194
            :|.||:|..||||..|.|...||.||.|.||.      .|.||..|     |||.|:.:|:|:||
 Worm   126 NIQYGSGECSGYLGTDTVEIGGLKIQKQEFGV------ANIVDYDFGTRPIDGIFGLAWPALSVD 184

  Fly   195 GVTPTFQNMMQQGLVQSPVFSFFL--RD-------NGSVTFYGGELILGGSDPSLYSGSLTYVNV 250
            .|||..||::.|..:.:|:|:.|.  ||       ||.:|:       ||.|....:.:::||.|
 Worm   185 QVTPPMQNLVSQNQLDAPIFTIFFDKRDPDYYYPSNGLITY-------GGLDTKNCNANISYVPV 242

  Fly   251 VQAAYWKFQTDYIKVGSTSISTFA-QAIADTGTSLIIAPQAQYDQISQLFNAN-----SEGLFEC 309
            ....||:|:.|..:||:.:.:... |||.|||:|....|.:....|:...||.     |.....|
 Worm   243 SSKTYWQFKVDGFQVGTYNRTVNRDQAIMDTGSSWFGLPYSVIAGIATQTNATWDLYASVYTVPC 307

  Fly   310 SS-TSYPDLIININGVDFKIPAKYYIIE---EEDFCSLAIQSINQDFW----IMGDVFLGRIYTE 366
            |: .|.|||:..|....|.|.|..|:.:   ::..|:||:..|:...:    .:|::|:.|..:.
 Worm   308 STMNSLPDLVFTIGAEKFPISAPEYVEDVGLDDGTCALAMYGIDASGFGPSVTLGNIFIRRYCSV 372

  Fly   367 FDVGNQRLGFAPV---NSAV 383
            |||||.|:|||..   ||.:
 Worm   373 FDVGNARIGFADAIHPNSVI 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	121/345 (35%)
		Asp	76..379	CDD:278455	121/337 (36%)
asp-18	NP_507653.2	Asp	63..385	CDD:365818	121/335 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162060
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860