Protein Alignment Pgcl and hrg-7

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001256448.1
• Gene: hrg-7 / 182635
• WormBaseID: WBGene00007605
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 124/440 - (28%)
• Similarity: 202/440 - (45%)
• Gaps: 79/440 - (17%)

  Fly     6 IKSLVFLAGLIVLVGEANSTLRRIPIQKSPNFKR--SHKNIVA----ERDFVQQKYNRQYTANGY 64
            :|:.:.|..|:.:|   ::.:.:..|...||.::  :.|..:|    ||:.:..|.:.|..::..
 Worm     1 MKTFIALLALLTVV---SAEVHQFNIGYRPNMRQRMNAKGKLAEYEKERNELLSKKSLQLASSSS 62

  Fly    65 PMEHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVP------------GSSCIST------ 111
            |   :.:|::..|...||:|:|.|:|::..|:||||||||            ||.|.||
 Worm    63 P---VIDYEDMAYMVQISLGSPAQNFVLFIDSGSSNLWVPDITCAGGKDATCGSYCKSTPYDACL 124

  Fly   112 ----------------------ACQDHQVFYKNKSSTYVANGTAFSITYGTGSVSGYLSVDCVGF 154
                                  |||....|..:.||:||.||..|.:||.||.|.|:..||...|
 Worm   125 TFCQEECCTKTVEGVKVLSTTDACQSKHRFNSSLSSSYVTNGQKFDMTYNTGEVKGFFGVDTFCF 189

  Fly   155 AGLTI--QSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVTPTFQNMMQQGLVQSPVFSFF 217
            ...::  ..|.||:.|| .|..|.....|||:|:|:|:|||:..||...|:|.||.:..|.|..:
 Worm   190 TNTSVCATGQVFGQATT-IGEAFAKQPEDGIIGLGWPALAVNQQTPPLFNLMNQGKLDQPYFVVY 253

  Fly   218 LRDNGSVT-FYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTDYIKVGSTSISTFA------- 274
            |.:.|..: ..||...:||.|.:..|.::.:|.:....:|:|     |:|..|..:::
 Worm   254 LANIGPTSQINGGAFTVGGLDTTHCSSNVDWVPLSTQTFWQF-----KLGGVSSGSYSQAPNSGW 313

  Fly   275 QAIADTGTSLIIAPQAQYDQISQLFNAN---SEGLF--ECSSTSYPDLIININGVDFKIPAKYYI 334
            ||.|||..|.|.||::....:::...|.   ..|.|  :|.:. .||::..|||..:.:|:..::
 Worm   314 QAAADTAASFIGAPKSVVTSLAKAVGATYVPLTGAFFMDCDAV-VPDIVFTINGKTYNMPSTSFV 377

  Fly   335 IEE-EDFCSLAIQSIN----QDFWIMGDVFLGRIYTEFDVGNQRLGFAPV 379
            :.. ...|..|...:.    ...|::|..|:.......|:.:.|||.|.|
 Worm   378 VSAGPGPCMFAFYELTAGGFYPAWMLGPPFMRAYCHVHDMKSGRLGLAKV 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	108/370 (29%)
		Asp	76..379	CDD:278455	108/362 (30%)
hrg-7	NP_001256448.1	pepsin_retropepsin_like	71..427	CDD:416259	108/362 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020