Protein Alignment Pgcl and asp-4

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_510191.1
• Gene: asp-4 / 181444
• WormBaseID: WBGene00000217
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 152/414 - (36%)
• Similarity: 211/414 - (50%)
• Gaps: 40/414 - (9%)

  Fly     9 LVFLAGLIVLVG----EANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQK--YNRQYTANG---- 63
            |:.|..|:::.|    :....||.:.::|.|..:.:.....:...|.:.:  |.:....||
 Worm     6 LLLLGALLLVQGLHVHKRQQKLRTVSLKKQPTLRETLLQAGSFETFAKHRHGYKKYLKTNGNHHF 70

  Fly    64 --YPM--------EHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSC--ISTACQDH 116
              |..        |.|.||.:.||:|.||||||.|:|.|.|||||||||:|...|  ...||..|
 Worm    71 DKYQALNVEGEIDELLRNYMDAQYFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFYDIACMLH 135

  Fly   117 QVFYKNKSSTYVANGTAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFD 181
            ..:....||||..:|...:|.|||||:.|::|.|.|..||:..:.|.|.|.|:|.|..||.|.||
 Worm   136 HRYDSKSSSTYKEDGRKMAIQYGTGSMKGFISKDSVCVAGVCAEDQPFAEATSEPGITFVAAKFD 200

  Fly   182 GILGMGFPSLAVDGVTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLT 246
            |||||.:|.:||.||.|.|..:.:|..|.|.:|||:|..|.. :..|||:..||.|...|...:|
 Worm   201 GILGMAYPEIAVLGVQPVFNTLFEQKKVPSNLFSFWLNRNPD-SEIGGEITFGGIDSRRYVEPIT 264

  Fly   247 YVNVVQAAYWKFQTDYIKVGS--TSISTFAQAIADTGTSLIIAPQAQYDQISQLFNA----NSEG 305
            ||.|.:..||:|:.|.: |||  ...|...|||||||||||..|:||.:.|.....|    ..|.
 Worm   265 YVPVTRKGYWQFKMDKV-VGSGVLGCSNGCQAIADTGTSLIAGPKAQIEAIQNFIGAEPLIKGEY 328

  Fly   306 LFECSST-SYPDLIININGVDFKIPAKYYIIE----EEDFCSLAIQSIN-----QDFWIMGDVFL 360
            :..|... :.|.:...|.|.:|.:..:.|:::    .:..|......|:     .:.||:||||:
 Worm   329 MISCDKVPTLPPVSFVIGGQEFSLKGEDYVLKVSQGGKTICLSGFMGIDLPERVGELWILGDVFI 393

  Fly   361 GRIYTEFDVGNQRLGFAPVNSAVG 384
            ||.|:.||....|:|||...:|.|
 Worm   394 GRYYSVFDFDQNRVGFAQAKTADG 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	136/328 (41%)
		Asp	76..379	CDD:278455	133/320 (42%)
asp-4	NP_510191.1	pepsin_retropepsin_like	88..411	CDD:386101	134/324 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890