Protein Alignment Pgcl and asp-17

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_741673.1
• Gene: asp-17 / 180250
• WormBaseID: WBGene00012683
• Length: 391
• Species: Caenorhabditis elegans
• Alignment Length: 393
• Identity: 127/393 - (32%)
• Similarity: 200/393 - (50%)
• Gaps: 34/393 - (8%)

  Fly     9 LVFLAGLIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQKYNRQYTANGYPMEHLSNYD 73
            |:|   |:.|....::.:.::|.:.:.:.:.........::|:..::..:......|   :|:|.
 Worm     3 LIF---LLFLAPFCSAAVFQLPTKSTGSLRAKLIRAGKYQEFLITQHAARLNTISQP---ISDYS 61

  Fly    74 NFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQ-------DHQVFYKNKSSTYVANG 131
            :..|.||.::|||.|...:..||||:|:||..:||.:..|.       ..|.|..:|||::....
 Worm    62 DEVYLGNFTVGTPPQPVSLVLDTGSANMWVIDASCDNMFCNGWIGSNYTRQKFDTSKSSSFSREN 126

  Fly   132 TAFSITYGTGSVSGYLSVDCVGF-AGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDG 195
            ..|||.||.|..||||..|.||. .||||:.|..| :..:...:|.....|||.|:.:|:||||.
 Worm   127 RKFSIQYGKGLCSGYLGTDTVGLGGGLTIRKQELG-IANKLDVDFAVQPMDGIFGLAWPALAVDQ 190

  Fly   196 VTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGE---LILGGSDPSLYSGSLTYVNVVQAAYWK 257
            :||..||::.|  :..||||.:| |......:||.   :..||.|.......:|||.:....||:
 Worm   191 ITPPMQNLISQ--LDVPVFSVWL-DRKIQASHGGSAGMITYGGIDTKNCDAGVTYVPLTAKTYWQ 252

  Fly   258 FQTDYIKVGSTSISTFAQAIADTGTSLIIAPQAQYDQISQLFNANSEGLFE-----CSS-TSYPD 316
            |:.|...||:.|...:.|.|:|||:|.|.||.|..:.|:...:|..:.:.|     ||: .:.||
 Worm   253 FKMDGFAVGTYSQYGYNQVISDTGSSWISAPYAMINDIATQTHATWDEMNEIYTVKCSTMKTQPD 317

  Fly   317 LIININGVDFKIPAKYYIIE---EEDFCSLAIQSINQD----FWIMGDVFLGRIYTEFDVGNQRL 374
            |:..|.|..|.:.:..||::   :|..|:|||..:...    .||:||||:.:....:|:||.|:
 Worm   318 LVFTIGGALFPVKSVEYILDIGLDEGKCALAISPLMASGFGPSWILGDVFIRQYCNIYDIGNARI 382

  Fly   375 GFA 377
            |||
 Worm   383 GFA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	120/335 (36%)
		Asp	76..379	CDD:278455	118/326 (36%)
asp-17	NP_741673.1	Asp	65..387	CDD:365818	118/325 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162076
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860