Protein Alignment Pgcl and asp-12

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_505134.1
• Gene: asp-12 / 179210
• WormBaseID: WBGene00017678
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 393
• Identity: 132/393 - (33%)
• Similarity: 206/393 - (52%)
• Gaps: 37/393 - (9%)

  Fly    12 LAGLIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAERD----FVQQK-----YNRQYTANGYPME 67
            |...:.::|..::|:    :|....::.|.|..:..|.    :||.|     .|....|:.  .:
 Worm     5 LLAFVAILGMCSATV----VQHKLIYRESPKMQMMRRGEWGAYVQHKAALRDANPAVFASA--PQ 63

  Fly    68 HLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKSSTYVANGT 132
            :::::.:.:|.|||:||||.|.|:|..||||:|||||||:|..| |:....|..:||:|:..||.
 Worm    64 NVNDFGDVEYLGNITIGTPPQQFIVVLDTGSANLWVPGSNCDGT-CKGKSEFDSSKSTTFKKNGQ 127

  Fly   133 AFSITYGTGSVSGYLSVDCVGFAG-----LTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLA 192
            ::.|.|.:||..|.:.||.|.|.|     |.:.|.||| :.:...:||.:...:||||:.|.|||
 Worm   128 SWQIQYESGSAKGIMGVDTVAFGGASEQQLLVPSTTFG-IASHISSNFKNDAAEGILGLAFTSLA 191

  Fly   193 VDGVTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGS-LTYVNVVQAAYW 256
            ||||||...|.:.:.::..|:|:.||...|:....||.:...|:..:...|. :.|..:..|.|:
 Worm   192 VDGVTPPLINAINKKILDQPLFTVFLEHKGTAKNVGGGVFTYGAVDTTNCGPVIAYQPLSSATYY 256

  Fly   257 KFQTDYIKVGSTSISTFAQAIADTGTSLIIAPQAQYDQISQL----FNANSEGLFECSSTSYPDL 317
            :|..|..|:||.|.:..:|.|:|||:|||..|.|..:..:|.    ::::.:..:...|||...|
 Worm   257 QFVADGFKLGSYSNNKKSQVISDTGSSLIGGPSAVINGFAQALGAKYHSDDDAYYLPCSTSKGTL 321

  Fly   318 IININGVDFKIPAKYYIIE--EEDFCSLAIQSINQDF------WIMGDVFLGRIYTEFDVGNQRL 374
            .|.|.|..:.|....||::  ..|.|..|..|.  ||      ||.||.|:.:....:|:|.||:
 Worm   322 DITIGGNVYSIEPVNYILDVGMGDTCVFAAFSF--DFGGFGPSWIFGDPFIRQYCNIYDIGQQRI 384

  Fly   375 GFA 377
            |||
 Worm   385 GFA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	120/329 (36%)
		Asp	76..379	CDD:278455	120/320 (38%)
asp-12	NP_505134.1	Asp	72..388	CDD:365818	120/320 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162020
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850