Protein Alignment l(1)sc and HAND1

DIOPT Version :9

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_004812.1
• Gene: HAND1 / 9421
• HGNCID: 4807
• Length: 215
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 43/203 - (21%)
• Similarity: 63/203 - (31%)
• Gaps: 67/203 - (33%)

  Fly    26 HQHHHQTQQHQLI-----------------------------APKIPLGTSQLQNMQQSQQSNVG 61
            |.|||....|.::                             ||..|.|               |
Human    11 HHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAG---------------G 60

  Fly    62 PMLSSQKKKFNYNNMPYGEQLPS--------VARRNA----RERNRVKQVNNGFVNLRQHLPQTV 114
            |..::......|.......|.|.        :.||..    :||.|.:.:|:.|..||:.:|...
Human    61 PPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVP 125

  Fly   115 VNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYND 179
            .::          ||||:.|||:|..||..|.|:|.....|.....: .|:....||...:....
Human   126 ADT----------KLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAF-KAELKKADGGRESKRKR 179

  Fly   180 SLDSSQQF 187
            .|...:.|
Human   180 ELQQHEGF 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	15/49 (31%)
		Peptidase_C11	<128..218	CDD:304483	19/60 (32%)
HAND1	NP_004812.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..109		14/70 (20%)
		bHLH_TS_HAND1	94..153	CDD:381522	23/68 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..198		4/22 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810