Protein Alignment l(1)sc and Ascl3

DIOPT Version :10

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_064435.1
• Gene: Ascl3 / 56787
• MGIID: 1928820
• Length: 174
• Species: Mus musculus
• Alignment Length: 132
• Identity: 40/132 - (30%)
• Similarity: 57/132 - (43%)
• Gaps: 41/132 - (31%)

  Fly    38 IAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLP------------------- 83
            :.|:.|:..|....:         |:|.........||  ||:..|
Mouse    38 LCPETPVPASYTDEL---------PLLPFSSDTLIMNN--YGDPYPFPFPMPYTNYRRCDYTYGP 91

  Fly    84 -SVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQD 147
             .:.:||.|||.|||.||.|:..||:|||:..:          .|:||||:|||.|::||..||.
Mouse    92 AFIRKRNERERQRVKCVNEGYARLRRHLPEDYL----------EKRLSKVETLRAAIKYISYLQS 146

  Fly   148 ML 149
            :|
Mouse   147 LL 148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	bHLH_TS_dAS-C_like	94..149	CDD:381587	24/54 (44%)
Ascl3	NP_064435.1	bHLH_TS_ASCL3	90..148	CDD:381588	29/67 (43%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	92..105		5/12 (42%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	106..144		20/47 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..174