Protein Alignment l(1)sc and ASCL3

DIOPT Version :10

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_065697.1
• Gene: ASCL3 / 56676
• HGNCID: 740
• Length: 181
• Species: Homo sapiens
• Alignment Length: 134
• Identity: 41/134 - (30%)
• Similarity: 54/134 - (40%)
• Gaps: 39/134 - (29%)

  Fly    72 NYNNMPYGEQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLR 136
            ||....|........:||.|||.|||.||.|:..||.|||:..:          .|:||||:|||
Human    82 NYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYL----------EKRLSKVETLR 136

  Fly   137 IAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLTGATQSAQSHSYH 201
            .|::||..||.:|           |....|:.|:                  .|...|..:.:.|
Human   137 AAIKYINYLQSLL-----------YPDKAETKNN------------------PGKVSSMIATTSH 172

  Fly   202 SASP 205
            .|.|
Human   173 HADP 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	bHLH_TS_dAS-C_like	94..149	CDD:381587	24/54 (44%)
ASCL3	NP_065697.1	bHLH_TS_ASCL3	91..149	CDD:381588	29/67 (43%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	93..106		5/12 (42%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	107..145		20/47 (43%)