Protein Alignment l(1)sc and NEUROD1

DIOPT Version :10

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_002491.3
• Gene: NEUROD1 / 4760
• HGNCID: 7762
• Length: 356
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 44/182 - (24%)
• Similarity: 73/182 - (40%)
• Gaps: 44/182 - (24%)

  Fly    61 GP----MLSSQKKKFNYNNMPYGEQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNG 121
            ||    |..::.::|....|          :.|||||||:..:|....|||:.:|
Human    85 GPKKKKMTKARLERFKLRRM----------KANARERNRMHGLNAALDNLRKVVP---------- 129

  Fly   122 GRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTA----SSTRHIYNSADESS----------NDGS 172
            ....::||||::|||:|..||..|.::|..|.:    |..:.:.....:.:          |..:
Human   130 CYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRT 194

  Fly   173 SYNDYNDSLDSSQQFLTGATQSAQSHSYHSAS---PTPSYSGSEISGGGYIK 221
            ...:.|..:   ...|..|:.|...|.|...|   |:|.|...:.|...::|
Human   195 FLPEQNQDM---PPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVFHVK 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	bHLH_TS_dAS-C_like	94..149	CDD:381587	18/54 (33%)
NEUROD1	NP_002491.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..94		3/8 (38%)
		bHLH_TS_NeuroD1	75..160	CDD:381562	29/94 (31%)
		Nuclear localization signal. /evidence=ECO:0000255	87..93		1/5 (20%)
		Neuro_bHLH	160..284	CDD:463621	15/87 (17%)