DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)sc and MYF6

DIOPT Version :9

Sequence 1:	NP_476623.1	Gene:	l(1)sc / 30983	FlyBaseID:	FBgn0002561	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_002460.1	Gene:	MYF6 / 4618	HGNCID:	7566	Length:	242	Species:	Homo sapiens

Alignment Length:	171	Identity:	47/171 - (27%)
Similarity:	73/171 - (42%)	Gaps:	31/171 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 RRNA---RERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDM 148
            ||.|   |||.|:|::|..|..|::   :||.|        .:::|.||:.||.|:.||..|||:
Human    94 RRKAATLRERRRLKKINEAFEALKR---RTVAN--------PNQRLPKVEILRSAISYIERLQDL 147

  Fly   149 LDDGTASSTRHIYNSAD---ESSNDGSSYNDYNDSLDSSQQFLTGATQ--SAQSHSYHSASPTPS 208
            |         |..:..:   |...|..||....::|:.:....|.::|  |...|| .....|..
Human   148 L---------HRLDQQEKMQELGVDPFSYRPKQENLEGADFLRTCSSQWPSVSDHS-RGLVITAK 202

  Fly   209 YSGSEISGGGYIKQELQEQDLKFDSFDSFSDEQPDDEELLD 249
            ..|:.|....  ...|:......||..|...:.|..||:::
Human   203 EGGASIDSSA--SSSLRCLSSIVDSISSEERKLPCVEEVVE 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	15/49 (31%)
l(1)sc	NP_476623.1	Peptidase_C11	<128..218	CDD:304483	26/94 (28%)
MYF6	NP_002460.1	Basic	3..98	CDD:416335	2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..63
		bHLH_TS_MRF4_Myf6	93..156	CDD:381504	27/81 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910