DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)sc and Tal1

DIOPT Version :9

Sequence 1:	NP_476623.1	Gene:	l(1)sc / 30983	FlyBaseID:	FBgn0002561	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001101428.2	Gene:	Tal1 / 313507	RGDID:	1306748	Length:	329	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	52/204 - (25%)
Similarity:	76/204 - (37%)	Gaps:	48/204 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LIAPKIPLGTSQLQNMQQSQQS---------NVGPMLSSQKKKFNYNN------MPYGEQL---- 82
            |.||..| |.:.|.::.|...|         :..||       |..||      .||..::
  Rat   126 LAAPAGP-GRALLYSLSQPLASLGSGFFGEPDAFPM-------FTNNNRVKRRPSPYEMEITDGP 182

  Fly    83 -PSVARR---NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIR 143
             ..|.||   |:|||.|.:.||..|..||:.:|.          ....|||||.:.||:|::||.
  Rat   183 HTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPT----------HPPDKKLSKNEILRLAMKYIN 237

  Fly   144 GLQDMLDDGTASSTRHIYNSADE-------SSNDGSSYNDYNDSLDSSQQFLTGATQSAQSHSYH 201
            .|..:|:|.....|:......|.       .:..|....|....:.|.......:...|.|...:
  Rat   238 FLAKLLNDQEEEGTQRAKPGKDPMVGAGGGGAGGGIPPEDLLQDVLSPNSSCGSSLDGAASPDSY 302

  Fly   202 SASPTPSYS 210
            :..|||.::
  Rat   303 TEEPTPKHT 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	16/49 (33%)
l(1)sc	NP_476623.1	Peptidase_C11	<128..218	CDD:304483	22/90 (24%)
Tal1	NP_001101428.2	bHLH_TS_TAL1	185..249	CDD:381549	27/73 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810