DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)sc and Lyl1

DIOPT Version :9

Sequence 1:	NP_476623.1	Gene:	l(1)sc / 30983	FlyBaseID:	FBgn0002561	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001007678.1	Gene:	Lyl1 / 304663	RGDID:	1359244	Length:	278	Species:	Rattus norvegicus

Alignment Length:	135	Identity:	41/135 - (30%)
Similarity:	57/135 - (42%)	Gaps:	26/135 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLQHQHHHQTQQHQLIAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLPSVAR 87
            |..|.|.|.......|.|..|.  |...|.:..::.:.|.:           ::..|.|...|||
  Rat    99 LALHYHPHPFLNSVYIGPAGPF--SIFPNSRLKRRPSHGEL-----------DLVDGHQPQKVAR 150

  Fly    88 R---NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDML 149
            |   |:|||.|.:.||..|..||:.||.          ....:||||.:.||:|::||..|..:|
  Rat   151 RVFTNSRERWRQQHVNGAFAELRKLLPT----------HPPDRKLSKNEVLRLAMKYIGFLVRLL 205

  Fly   150 DDGTA 154
            .|..|
  Rat   206 RDQAA 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	16/49 (33%)
l(1)sc	NP_476623.1	Peptidase_C11	<128..218	CDD:304483	13/27 (48%)
Lyl1	NP_001007678.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..52
		HLH	155..207	CDD:197674	23/61 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..278
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810