Protein Alignment l(1)sc and ascl1a

DIOPT Version :10

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_571294.1
• Gene: ascl1a / 30466
• ZFINID: ZDB-GENE-980526-90
• Length: 196
• Species: Danio rerio
• Alignment Length: 238
• Identity: 77/238 - (32%)
• Similarity: 106/238 - (44%)
• Gaps: 72/238 - (30%)

  Fly    34 QHQLIAPKIPLGTSQLQ-------------NMQQSQQSNVGPMLSSQKKKFNYNNMPYG--EQLP 83
            |.|.:.|.....:..:|             :.|..:|.:..|.|...|::.|:....|.  :|.|
Zfish    13 QQQFMPPACFFASQSIQLSPTDSQCSNKSASKQAKRQRSSSPELLRCKRRLNFAGFGYSLPQQQP 77

  Fly    84 -SVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQD 147
             :|||||.|||||||.|||||..||:|:|        ||  .::||:|||:|||.||||||.||.
Zfish    78 HAVARRNERERNRVKLVNNGFATLREHVP--------NG--AANKKMSKVETLRSAVEYIRALQQ 132

  Fly   148 MLDDGTASSTRHIYNSADESSNDGSSY-NDYNDSLDSSQQFLTGATQSAQSHSYHSASPTPSYSG 211
            :||:..|.|.  .:.|...|.....:| ||.|..                     :.||..|||.
Zfish   133 LLDEHDAVSA--AFQSGVLSPTISQNYSNDMNSM---------------------AGSPVSSYSS 174

  Fly   212 SEISGGGYIKQELQEQDLKFDSFDSFSDEQPDDEELLDYISSW 254
            .|                  .|:|..|   |:::||||: ::|
Zfish   175 DE------------------GSYDPLS---PEEQELLDF-TNW 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	bHLH_TS_dAS-C_like	94..149	CDD:381587	31/54 (57%)
ascl1a	NP_571294.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..54		2/20 (10%)
		bHLH_TS_ASCL1_Mash1	75..145	CDD:381585	45/81 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..186		13/68 (19%)