DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)sc and Mesp2

DIOPT Version :9

Sequence 1:	NP_476623.1	Gene:	l(1)sc / 30983	FlyBaseID:	FBgn0002561	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001099743.1	Gene:	Mesp2 / 293046	RGDID:	1305959	Length:	368	Species:	Rattus norvegicus

Alignment Length:	163	Identity:	43/163 - (26%)
Similarity:	67/163 - (41%)	Gaps:	32/163 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 NVGPMLSSQKKKFNYNNMPYGEQLPSVARRNA---RERNRVKQVNNGFVNLRQHLPQTVVNSLSN 120
            :.||..|::..:...|........|:..:|.:   ||:.|::.:......||:.||.:|.
  Rat    54 STGPARSARNTQVAPNAPRRARPAPAGGQRQSASEREKLRMRTLARALQELRRFLPPSVA----- 113

  Fly   121 GGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADES-SNDGSSYNDYNDSLDSS 184
               .:.:.|:|::|||:|:.||..|..:|.....|..|....|||.: |:......|  ||..|.
  Rat   114 ---PAGQSLTKIETLRLAIRYIGHLSALLGLSEDSLRRRRRRSADAAFSHRCPQCPD--DSSPSQ 173

  Fly   185 QQFLTGATQSAQSHSYHSASPTPSYSGSEISGG 217
            .|.|                 .||. ||:||.|
  Rat   174 AQML-----------------GPSL-GSDISSG 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	13/49 (27%)
l(1)sc	NP_476623.1	Peptidase_C11	<128..218	CDD:304483	29/91 (32%)
Mesp2	NP_001099743.1	HLH	82..135	CDD:278439	17/60 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810