Protein Alignment l(1)sc and PTF1A

DIOPT Version :9

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_835455.1
• Gene: PTF1A / 256297
• HGNCID: 23734
• Length: 328
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 50/196 - (25%)
• Similarity: 81/196 - (41%)
• Gaps: 52/196 - (26%)

  Fly    80 EQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRG 144
            :||...|  |.|||.|::.:|:.|..||.|:|....          .|:||||||||:|:.||..
Human   162 QQLRQAA--NVRERRRMQSINDAFEGLRSHIPTLPY----------EKRLSKVDTLRLAIGYINF 214

  Fly   145 LQDM------LDDGTASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLTGATQSAQSHSYHSA 203
            |.::      |..|.|..          ....|.......||..|..|.:....:..:     |.
Human   215 LSELVQADLPLRGGGAGG----------CGGPGGGGRLGGDSPGSQAQKVIICHRGTR-----SP 264

  Fly   204 SPT-PSYSGSEISGGGYI---KQELQEQDL-------------KFDSFDSFSDEQPDDEELLDYI 251
            ||: |.|....::|....   :::|:||::             |.:|..||::  .::|...:::
Human   265 SPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRKLNSKSSFNN--IENEPPFEFV 327

  Fly   252 S 252
            |
Human   328 S 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	18/49 (37%)
		Peptidase_C11	<128..218	CDD:304483	26/96 (27%)
PTF1A	NP_835455.1	HLH	165..220	CDD:238036	25/66 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..278		5/23 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810