DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)sc and Tcf21

DIOPT Version :9

Sequence 1:	NP_476623.1	Gene:	l(1)sc / 30983	FlyBaseID:	FBgn0002561	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001027569.1	Gene:	Tcf21 / 252856	RGDID:	620523	Length:	179	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	44/161 - (27%)
Similarity:	68/161 - (42%)	Gaps:	24/161 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GTSQLQNMQQSQQSNVGPMLS----SQKKKFNYNNMPY------GEQLPSVARRNARERNRVKQV 99
            |||.....:.|...|..|...    .:::|......|.      |:|:...| .|||||.|::.:
  Rat    32 GTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNA-ANARERARMRVL 95

  Fly   100 NNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDML-DDGTASSTRHIYNS 163
            :..|..|:..||....::          ||||:||||:|..||..|:.:| :|...:...|..|.
  Rat    96 SKAFSRLKTTLPWVPPDT----------KLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNL 150

  Fly   164 ADESSNDGSSYNDYNDSLDSSQQFLTGATQS 194
            .......|...:|..:.:.:|:  |.|.|.|
  Rat   151 TWPFMVAGKPESDLKEVVTASR--LCGTTAS 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	15/49 (31%)
l(1)sc	NP_476623.1	Peptidase_C11	<128..218	CDD:304483	23/68 (34%)
Tcf21	NP_001027569.1	bHLH_TS_TCF21_capsulin	77..140	CDD:381547	26/73 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810