DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(1)sc and Twist1

DIOPT Version :10

Sequence 1:NP_476623.1 Gene:l(1)sc / 30983 FlyBaseID:FBgn0002561 Length:257 Species:Drosophila melanogaster
Sequence 2:NP_035788.1 Gene:Twist1 / 22160 MGIID:98872 Length:206 Species:Mus musculus


Alignment Length:72 Identity:26/72 - (36%)
Similarity:33/72 - (45%) Gaps:16/72 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGL-----QDM 148
            |.|||.|.:.:|..|..||:.:|..           .|.||||:.||::|..||..|     .|.
Mouse   118 NVRERQRTQSLNEAFAALRKIIPTL-----------PSDKLSKIQTLKLAARYIDFLYQVLQSDE 171

  Fly   149 LDDGTAS 155
            ||...||
Mouse   172 LDSKMAS 178

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(1)scNP_476623.1 bHLH_TS_dAS-C_like 94..149 CDD:381587 18/59 (31%)
Twist1NP_035788.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..109
bHLH_TS_TWIST1 102..178 CDD:381418 24/70 (34%)
Sufficient for transactivation activity 165..195 5/14 (36%)
Blue background indicates that the domain is not in the aligned region.

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