Protein Alignment l(1)sc and Ascl2

DIOPT Version :9

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_032580.2
• Gene: Ascl2 / 17173
• MGIID: 96920
• Length: 263
• Species: Mus musculus
• Alignment Length: 281
• Identity: 76/281 - (27%)
• Similarity: 110/281 - (39%)
• Gaps: 77/281 - (27%)

  Fly     5 CSSKFQQQHYQLTNSNIFLLQH---QHHHQTQQHQLIA---------------PKIPLGTSQLQN 51
            |||...:..   ..:|:....|   :.|......:|:|               |::...:|.:..
Mouse    25 CSSALPEAR---EGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDGGALPRLMPTSSGVAG 86

  Fly    52 MQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVN 116
            ...:::....|.|....::.............:|||||.|||||||.||.||..||||:|.
Mouse    87 ACAARRRQASPELLRCSRRRRSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPH---- 147

  Fly   117 SLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYNDSL 181
                  .|::||||||:|||.||||||.||.:|.:          :.|..::..|..........
Mouse   148 ------GGANKKLSKVETLRSAVEYIRALQRLLAE----------HDAVRAALAGGLLTPATPPS 196

  Fly   182 DSSQQFLTGATQSAQSHSYHSASPTP-------------SYSGSEISGGGYIKQELQEQDLKFDS 233
            |...|  ..|:.::.|.|..|.||:|             :||..|.|..|.:
Mouse   197 DECAQ--PSASPASASLSCASTSPSPDRLGCSEPTSPRSAYSSEESSCEGEL------------- 246

  Fly   234 FDSFSDEQPDDEELLDYISSW 254
                   .|.::||||: |||
Mouse   247 -------SPMEQELLDF-SSW 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	27/49 (55%)
		Peptidase_C11	<128..218	CDD:304483	32/102 (31%)
Ascl2	NP_032580.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..126		5/21 (24%)
		HLH	134..176	CDD:197674	28/51 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..248		14/75 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848573
Domainoid	1	1.000	67	1.000	Domainoid score	I9760
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I5162
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001993
OrthoInspector	1	1.000	-	-		mtm11115
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13935
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2717
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.850