Protein Alignment l(1)sc and Hand1

DIOPT Version :9

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_032239.1
• Gene: Hand1 / 15110
• MGIID: 103577
• Length: 216
• Species: Mus musculus
• Alignment Length: 222
• Identity: 45/222 - (20%)
• Similarity: 71/222 - (31%)
• Gaps: 83/222 - (37%)

  Fly    26 HQHHHQTQQHQLI-----------------------------APKIPLGTSQLQNMQQSQQSNVG 61
            |.|||....|.::                             ||..|.|               |
Mouse    11 HHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAG---------------G 60

  Fly    62 PMLSSQKKKFNY------NNMP-----YGEQLPSVARRNA---RERNRVKQVNNGFVNLRQHLPQ 112
            |..::......|      :..|     .|.:||.  |:.:   :||.|.:.:|:.|..||:.:|.
Mouse    61 PPPTTAVAAAAYGPDARPSQSPGRLEALGSRLPK--RKGSGPKKERRRTESINSAFAELRECIPN 123

  Fly   113 TVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDY 177
            ...::          ||||:.|||:|..||..|.|:|             :.|..:.|..::...
Mouse   124 VPADT----------KLSKIKTLRLATSYIAYLMDVL-------------AKDAQAGDPEAFKAE 165

  Fly   178 NDSLDSSQQFLTGATQSAQSHSYHSAS 204
            ....|..::.........|..|:..||
Mouse   166 LKKTDGGRESKRKRELPQQPESFPPAS 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	HLH	<96..146	CDD:278439	15/49 (31%)
		Peptidase_C11	<128..218	CDD:304483	20/77 (26%)
Hand1	NP_032239.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		4/8 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..109		15/72 (21%)
		HLH	103..152	CDD:197674	21/71 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..203		5/28 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810