DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(1)sc and Atoh1

DIOPT Version :10

Sequence 1:NP_476623.1 Gene:l(1)sc / 30983 FlyBaseID:FBgn0002561 Length:257 Species:Drosophila melanogaster
Sequence 2:NP_031526.1 Gene:Atoh1 / 11921 MGIID:104654 Length:351 Species:Mus musculus


Alignment Length:181 Identity:49/181 - (27%)
Similarity:74/181 - (40%) Gaps:52/181 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 PYGEQLPSVARR-----NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLR 136
            |..:|:..|.::     |||||.|:..:|:.|..||..:|     |.:|     .|||||.:||:
Mouse   145 PSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIP-----SFNN-----DKKLSKYETLQ 199

  Fly   137 IAVEYIRGLQDMLD---------DGTASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLTGAT 192
            :|..||..|.::|.         ..|||.....::....||.:|.:                ||:
Mouse   200 MAQIYINALSELLQTPNVGEQPPPPTASCKNDHHHLRTASSYEGGA----------------GAS 248

  Fly   193 QSAQSHSYHSASPTPS--------YSGSEISGGGYIKQELQEQDLKFDSFD 235
            ..|.:.......|.|:        :|| ..|.|||   .:|...|.|.:|:
Mouse   249 AVAGAQPAPGGGPRPTPPGPCRTRFSG-PASSGGY---SVQLDALHFPAFE 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(1)scNP_476623.1 bHLH_TS_dAS-C_like 94..149 CDD:381587 19/54 (35%)
Atoh1NP_031526.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..39
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..116
bHLH_TS_ATOH1 152..215 CDD:381556 26/72 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 244..278 7/50 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 308..351
Blue background indicates that the domain is not in the aligned region.

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