Protein Alignment l(1)sc and TWIST2

DIOPT Version :10

• Sequence 1: NP_476623.1
• Gene: l(1)sc / 30983
• FlyBaseID: FBgn0002561
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_476527.1
• Gene: TWIST2 / 117581
• HGNCID: 20670
• Length: 160
• Species: Homo sapiens
• Alignment Length: 155
• Identity: 36/155 - (23%)
• Similarity: 58/155 - (37%)
• Gaps: 50/155 - (32%)

  Fly    38 IAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLPSVARR-------------- 88
            ::|...||||:.:..:|       |....:|::::..:...|...|....:
Human     9 VSPVDSLGTSEEELERQ-------PKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQS 66

  Fly    89 -----NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDM 148
                 |.|||.|.:.:|..|..||:.:|..           .|.||||:.||::|..||..|..:
Human    67 QRILANVRERQRTQSLNEAFAALRKIIPTL-----------PSDKLSKIQTLKLAARYIDFLYQV 120

  Fly   149 LDDGTASSTRHIYNSADESSNDGSS 173
            |             .:||..|..:|
Human   121 L-------------QSDEMDNKMTS 132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)sc	NP_476623.1	bHLH_TS_dAS-C_like	94..149	CDD:381587	17/54 (31%)
TWIST2	NP_476527.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		10/60 (17%)
		bHLH_TS_TWIST2	51..132	CDD:381543	25/104 (24%)