DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(1)sc and ascl2

DIOPT Version :9

Sequence 1:NP_476623.1 Gene:l(1)sc / 30983 FlyBaseID:FBgn0002561 Length:257 Species:Drosophila melanogaster
Sequence 2:XP_002940290.3 Gene:ascl2 / 100494131 XenbaseID:XB-GENE-6458615 Length:236 Species:Xenopus tropicalis


Alignment Length:175 Identity:60/175 - (34%)
Similarity:83/175 - (47%) Gaps:37/175 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 PKIPLG--TSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPY-------GEQLPSV-------ARR 88
            |.:|:.  :|.::....|::....|     :|..|.:..|.       ...||:.       .||
 Frog    57 PVVPVAPPSSAMEEQPGSERPAKAP-----RKVANQSGSPQRLRCQRRSGSLPNAIGISATSERR 116

  Fly    89 NARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGT 153
            |.|||||||.||.||..||||:||         .:|.:||:|||:|||.||||||.||.:|.:.|
 Frog   117 NERERNRVKLVNLGFAKLRQHVPQ---------AQGPNKKMSKVETLRSAVEYIRALQSILMERT 172

  Fly   154 ASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLT-GATQSAQS 197
            |.      .....:.:||.|....:.|:||....|: |:..|..|
 Frog   173 AG------EGQGRAGSDGLSPCGSSCSVDSGSLALSPGSCSSCAS 211

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(1)scNP_476623.1 HLH <96..146 CDD:278439 27/49 (55%)
Peptidase_C11 <128..218 CDD:304483 28/71 (39%)
ascl2XP_002940290.3 bHLH_TS_ASCL2_Mash2 110..174 CDD:381586 39/72 (54%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 72 1.000 Domainoid score I9148
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 91 1.000 Inparanoid score I4952
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1131543at2759
OrthoFinder 1 1.000 - - FOG0001993
OrthoInspector 1 1.000 - - mtm9527
Panther 1 1.100 - - O PTHR13935
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3926
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
88.100

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