Protein Alignment sc and HAND2

DIOPT Version :9

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 116
• Identity: 39/116 - (33%)
• Similarity: 57/116 - (49%)
• Gaps: 29/116 - (25%)

  Fly    72 MALTRCSESVS-----------SLSPGSSPAPYNVDQSQSVQRR---NARERNRVKQVNNSFARL 122
            |||:...|..|           .:.||:.|.  .:...:.|:||   |.:||.|.:.:|::||.|
Human    60 MALSYSPEYASGAAGLDHSHYGGVPPGAGPP--GLGGPRPVKRRGTANRKERRRTQSINSAFAEL 122

  Fly   123 RQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLV--DDLNG 171
            |:.|| ::..|          .|:||:.|||:|..||..|.||:  ||.||
Human   123 RECIP-NVPAD----------TKLSKIKTLRLATSYIAYLMDLLAKDDQNG 162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	HLH	105..163	CDD:278439	21/57 (37%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		10/41 (24%)
		bHLH_TS_HAND2	100..161	CDD:381477	28/71 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810