DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sc and MSGN1

DIOPT Version :9

Sequence 1:	NP_476803.1	Gene:	sc / 30982	FlyBaseID:	FBgn0004170	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001099039.1	Gene:	MSGN1 / 343930	HGNCID:	14907	Length:	193	Species:	Homo sapiens

Alignment Length:	189	Identity:	46/189 - (24%)
Similarity:	70/189 - (37%)	Gaps:	63/189 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PTTINSATKIFRYQHIMPAPS---------PLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSES 80
            |..:|.|:.   .|.:.||||         |.:.|         :|.:      .|.|.:..||.
Human    35 PFELNQASP---SQSLSPAPSLESYSSSPCPAVAG---------LPCE------HGGASSGGSEG 81

  Fly    81 VS--------------------SLSPGSSP-APYNVDQSQSVQRR---NARERNRVKQVNNSFAR 121
            .|                    .|..|..| |........|||||   :.||:.|::.:.::...
Human    82 CSVGGASGLVEVDYNMLAFQPTHLQGGGGPKAQKGTKVRMSVQRRRKASEREKLRMRTLADALHT 146

  Fly   122 LRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNA 180
            ||.::|...       ..||  :.::|:.||:..::||..|.||   ||.|....|.:|
Human   147 LRNYLPPVY-------SQRG--QPLTKIQTLKYTIKYIGELTDL---LNRGREPRAQSA 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	HLH	105..163	CDD:278439	13/57 (23%)
MSGN1	NP_001099039.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..59		8/26 (31%)
MSGN1	NP_001099039.1	HLH	125..179	CDD:278439	15/62 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810