Protein Alignment sc and PTF1A

DIOPT Version :9

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_835455.1
• Gene: PTF1A / 256297
• HGNCID: 23734
• Length: 328
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 65/261 - (24%)
• Similarity: 102/261 - (39%)
• Gaps: 85/261 - (32%)

  Fly    49 PGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAP-------YNVDQSQSVQRRNA 106
            |||....|..  |.....|...|.|:......:..||..::.|.       ...:..|..|..|.
Human   108 PGGFPYSPGS--PPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANV 170

  Fly   107 RERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPH-KKISKVDTLRIAVEYIRRLQDLVD-DL 169
            |||.|::.:|::|..||.|||..            |: |::|||||||:|:.||..|.:||. ||
Human   171 RERRRMQSINDAFEGLRSHIPTL------------PYEKRLSKVDTLRLAIGYINFLSELVQADL 223

  Fly   170 -------------NGGSNIGANNAVTQLQ---LCLDESSSHSSSSSTCSS---------SGHNTY 209
                         .||..:|.::..:|.|   :|      |..:.|...|         :||:..
Human   224 PLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIIC------HRGTRSPSPSDPDYGLPPLAGHSLS 282

  Fly   210 YQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFN 274
            :.:         ::||:.|              |::.|:.       |.|.::.:..:| .||||
Human   283 WTD---------EKQLKEQ--------------NIIRTAK-------VWTPEDPRKLNS-KSSFN 316

  Fly   275 S 275
            :
Human   317 N 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	HLH	105..163	CDD:278439	24/58 (41%)
PTF1A	NP_835455.1	HLH	165..220	CDD:238036	27/66 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..278		2/18 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		5/14 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810