Protein Alignment sc and Ascl2

DIOPT Version :9

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_113691.1
• Gene: Ascl2 / 24209
• RGDID: 2159
• Length: 260
• Species: Rattus norvegicus
• Alignment Length: 186
• Identity: 66/186 - (35%)
• Similarity: 87/186 - (46%)
• Gaps: 47/186 - (25%)

  Fly    43 APSP----------LIPGG-------NQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSP 90
            ||.|          |:.||       ..:..||....:.|..:|.   |.|||....|   |::.
  Rat    54 APKPVAGAPALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPE---LLRCSRRRRS---GATE 112

  Fly    91 APYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIA 155
            |.   ..|.:|.|||.|||||||.||..|..||||:|..           |.:||:|||:|||.|
  Rat   113 AS---SSSAAVARRNERERNRVKLVNLGFQALRQHVPHG-----------GANKKLSKVETLRSA 163

  Fly   156 VEYIRRLQDLVDD-------LNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSSS 204
            |||||.||.|:.:       |:||.   ...|.....:|...|:|.:|:|.:|:|:
  Rat   164 VEYIRALQRLLAEHDAVRAALSGGL---LTPATRPSDVCTQPSASPASASLSCTST 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	HLH	105..163	CDD:278439	31/57 (54%)
Ascl2	NP_113691.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..126		16/49 (33%)
		HLH	134..176	CDD:197674	26/52 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..239		8/26 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352170
Domainoid	1	1.000	67	1.000	Domainoid score	I9554
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5061
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1131543at2759
OrthoFinder	1	1.000	-	-		FOG0001993
OrthoInspector	1	1.000	-	-		mtm9108
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.850