Protein Alignment sc and ASCL4

DIOPT Version :9

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_982260.3
• Gene: ASCL4 / 121549
• HGNCID: 24311
• Length: 172
• Species: Homo sapiens
• Alignment Length: 173
• Identity: 57/173 - (32%)
• Similarity: 88/173 - (50%)
• Gaps: 24/173 - (13%)

  Fly    42 PAPSPLIPGGNQNQP---AGTMPIKTRKYTPRGMAL---TRCSE-SVSSLSPGSSPAPYNVD--- 96
            ||....:|...:..|   .||:|...|: .|..:||   ..|.| :.|..:.|....|..:|
Human     6 PAERLALPYSLRTAPLGVPGTLPGLPRR-DPLRVALRLDAACWEWARSGCARGWQYLPVPLDSAF 69

  Fly    97 QSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRR 161
            :...:::||.|||.||:.||..:||||.|:|:.:           ..|::|||:|||.|::||:.
Human    70 EPAFLRKRNERERQRVRCVNEGYARLRDHLPREL-----------ADKRLSKVETLRAAIDYIKH 123

  Fly   162 LQDLVDDLNGGSNIGANNAVTQLQL-CLDESSSHSSSSSTCSS 203
            ||:|::....|.. ||..||.|.:. |..:..|.:||:.:.||
Human   124 LQELLERQAWGLE-GAAGAVPQRRAECNSDGESKASSAPSPSS 165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	HLH	105..163	CDD:278439	24/57 (42%)
ASCL4	NP_982260.3	bHLH_SF	66..129	CDD:412148	29/73 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..172		7/22 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41464
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13935
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910