Protein Alignment sc and Atoh1

DIOPT Version :10

• Sequence 1: NP_476803.1
• Gene: sc / 30982
• FlyBaseID: FBgn0004170
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_031526.1
• Gene: Atoh1 / 11921
• MGIID: 104654
• Length: 351
• Species: Mus musculus
• Alignment Length: 273
• Identity: 68/273 - (24%)
• Similarity: 97/273 - (35%)
• Gaps: 81/273 - (29%)

  Fly    50 GGNQNQPAGTMPIKTRKYTPR---GMALTR--CSESVSSLSPGSSPAPYNVDQSQSVQRR---NA 106
            ||....|.   |:|.|:...:   |:.:..  ||..       .:|:...|:..|. |||   ||
Mouse   110 GGLSKSPG---PVKVREQLCKLKGGVVVDELGCSRQ-------RAPSSKQVNGVQK-QRRLAANA 163

  Fly   107 RERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNG 171
            |||.|:..:|::|.:||..|| |...|          ||:||.:||::|..||..|.:|:...|.
Mouse   164 RERRRMHGLNHAFDQLRNVIP-SFNND----------KKLSKYETLQMAQIYINALSELLQTPNV 217

  Fly   172 GS-----NIGANNAVTQLQLCLDESSSHSSS-------------------------SSTCSSSGH 206
            |.     .....|....|:..........:|                         |...||.|:
Mouse   218 GEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAPGGGPRPTPPGPCRTRFSGPASSGGY 282

  Fly   207 NTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCV--STSKNQQTCH-- 267
            :.            |...|....|..:.|||:....:| ..|:|||....|  ..||.....|
Mouse   283 SV------------QLDALHFPAFEDRALTAMMAQKDL-SPSLPGGILQPVQEDNSKTSPRSHRS 334

  Fly   268 ----SPTSSFNSS 276
                ||.|.::.|
Mouse   335 DGEFSPHSHYSDS 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sc	NP_476803.1	bHLH_TS_dAS-C_like	100..166	CDD:381587	27/68 (40%)
Atoh1	NP_031526.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..39
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..116		2/5 (40%)
		bHLH_TS_ATOH1	152..215	CDD:381556	29/74 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..278		2/33 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	308..351		13/41 (32%)