Protein Alignment ac and NEUROD6

DIOPT Version :10

• Sequence 1: NP_476824.1
• Gene: ac / 30981
• FlyBaseID: FBgn0000022
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_073565.2
• Gene: NEUROD6 / 63974
• HGNCID: 13804
• Length: 337
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 49/200 - (24%)
• Similarity: 78/200 - (39%)
• Gaps: 54/200 - (27%)

  Fly    30 NARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVL 94
            |||||||:..:|:....||:.:|..              ...:||||:.||::|..||..|.::|
Human   100 NARERNRMHGLNDALDNLRKVVPCY--------------SKTQKLSKIETLRLAKNYIWALSEIL 150

  Fly    95 HENDQQKQKQLHLQQQHLHFQQQQQHQHLYAWHQELQLQS---PTGSTSSCNSISSYC------- 149
            ...   |:..|....|:|.....|...:|.|...:|..:|   ..|..::.::.|.|.
Human   151 RIG---KRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTFYPPYH 212

  Fly   150 KPATSTIPG--------ATPPNNFHTKLEASFEDYRNNSCSS------------------GTEDE 188
            .|..:|.||        :..|.|:.:..| ||.:..:..|:|                  ..:.|
Human   213 SPELTTPPGHGTLDNSKSMKPYNYCSAYE-SFYESTSPECASPQFEGPLSPPPINYNGIFSLKQE 276

  Fly   189 DILDY 193
            :.|||
Human   277 ETLDY 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ac	NP_476824.1	bHLH_TS_dAS-C_like	25..94	CDD:381587	21/63 (33%)
NEUROD6	NP_073565.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..82
		Nuclear localization signal. /evidence=ECO:0000255	80..86
		bHLH_TS_NeuroD6_ATOH2	82..151	CDD:381565	21/64 (33%)
		Neuro_bHLH	153..272	CDD:463621	23/122 (19%)