Protein Alignment ac and NEUROD4

DIOPT Version :10

• Sequence 1: NP_476824.1
• Gene: ac / 30981
• FlyBaseID: FBgn0000022
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_067014.2
• Gene: NEUROD4 / 58158
• HGNCID: 13802
• Length: 331
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 59/265 - (22%)
• Similarity: 89/265 - (33%)
• Gaps: 101/265 - (38%)

  Fly     2 ALGSENHSVFNDDEESSSA----FNGPSV---------------IRRNARERNRVKQVNNGFSQL 47
            :|..|:.|:..::||....    ..||..               ::.|||||.|:..:|:....|
Human    46 SLTEEHDSIEEEEEEEEDGEKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNL 110

  Fly    48 RQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVLHENDQQKQK--------- 103
            |:.:|..              ...:||||:.||::|..||..|.:||......:.|
Human   111 RRVMPCY--------------SKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKGFVEMLCKG 161

  Fly   104 -----------------QLHLQQQH------------LH-FQQQQQ--------HQHLYAWHQEL 130
                             |..|.::|            :| |..|..        |...:..|.:.
Human   162 LSQPTSNLVAGCLQLGPQSVLLEKHEDKSPICDSAISVHNFNYQSPGLPSPPYGHMETHLLHLKP 226

  Fly   131 QLQSPTGSTSSCNSISSYCKPATSTIP---GATPP----NNFHTK------LEASFE---DYRNN 179
            |:....|.:|..:.:     |..||.|   ..|||    .||..|      ||.|:.   .|.::
Human   227 QVFKSLGESSFGSHL-----PDCSTPPYEGPLTPPLSISGNFSLKQDGSPDLEKSYSFMPHYPSS 286

  Fly   180 SCSSG 184
            |.|||
Human   287 SLSSG 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ac	NP_476824.1	bHLH_TS_dAS-C_like	25..94	CDD:381587	20/83 (24%)
NEUROD4	NP_067014.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..80		7/33 (21%)
		bHLH_TS_NeuroD4_ATOH3	59..145	CDD:381564	26/99 (26%)
		Neuro_bHLH	146..264	CDD:463621	20/122 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..265		7/18 (39%)