DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ac and FIGLA

DIOPT Version :9

Sequence 1:	NP_476824.1	Gene:	ac / 30981	FlyBaseID:	FBgn0000022	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001004311.2	Gene:	FIGLA / 344018	HGNCID:	24669	Length:	219	Species:	Homo sapiens

Alignment Length:	176	Identity:	41/176 - (23%)
Similarity:	62/176 - (35%)	Gaps:	64/176 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SSAFNGPSVIRR----NARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVS 78
            ||..|...|:.|    ||:||.|:|.:|.||::|:..:|..              ..::|.|||.
Human    55 SSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFL--------------PQSRKPSKVD 105

  Fly    79 TLKMAVEYIRRLQKVLHENDQQKQKQLHLQQQHLHFQQQQQHQHLYAWHQELQLQSPTGSTSSCN 143
            .||.|.|||:.|..:|......|:                              |.|...:.|.|
Human   106 ILKGATEYIQVLSDLLEGAKDSKK------------------------------QDPDEQSYSNN 140

  Fly   144 SISSYCKPATSTIPGATPPNNFHTKLEASFEDYRNNSCSSGTEDED 189
            |..|:...|.......|                ::.||:.|.::|:
Human   141 SSESHTSSARQLSRNIT----------------QHISCAFGLKNEE 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ac	NP_476824.1	HLH	30..96	CDD:197674	23/65 (35%)
FIGLA	NP_001004311.2	HLH	65..122	CDD:238036	23/70 (33%)
FIGLA	NP_001004311.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..151		8/56 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810