DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ac and tal1

DIOPT Version :9

Sequence 1:	NP_476824.1	Gene:	ac / 30981	FlyBaseID:	FBgn0000022	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001135468.1	Gene:	tal1 / 100196924	XenbaseID:	XB-GENE-479827	Length:	388	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	55/213 - (25%)
Similarity:	83/213 - (38%)	Gaps:	80/213 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LGSENHSVFNDDEESSSAF------------------NGP--SVIRR---NARERNRVKQVNNGF 44
            |.|.|...| ||.|:...|                  .||  .|:||   |:|||.|.:.||..|
Frog   213 LASGNSGYF-DDPEAYPMFTNNSRVKRRPGPYEVEISEGPQTKVVRRIFTNSRERWRQQNVNGAF 276

  Fly    45 SQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVLHENDQQKQKQLHLQQ 109
            ::||:.||.              ...:|||||...|::|::||..|.|:|  :||:::..
Frog   277 AELRKLIPT--------------HPPDKKLSKNEILRLAMKYINFLAKLL--DDQEEEGN----- 320

  Fly   110 QHLHFQQQQQHQHLYAWHQELQLQSPTGSTSSCNSISSYCKPATSTIPGATPPNNFHTKLEASFE 174
                 |:.:.::......||| ||......|||.          |::.|...|:::
Frog   321 -----QRNKGNKDNGMVQQEL-LQDMLSPNSSCG----------SSLDGVPSPDSY--------- 360

  Fly   175 DYRNNSCSSGTEDEDILD 192
                      :|:.|.||
Frog   361 ----------SEEHDTLD 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ac	NP_476824.1	HLH	30..96	CDD:197674	24/65 (37%)
tal1	NP_001135468.1	PHA03247	<6..195	CDD:223021
tal1	NP_001135468.1	bHLH_TS_TAL1	254..318	CDD:381549	29/79 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910