DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment y and Rgn

DIOPT Version :9

Sequence 1:	NP_476792.1	Gene:	y / 30980	FlyBaseID:	FBgn0004034	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_113734.1	Gene:	Rgn / 25106	RGDID:	3560	Length:	299	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	37/191 - (19%)
Similarity:	64/191 - (33%)	Gaps:	64/191 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PVGVEHFGNRLFVTVP-----RW--------RDGIPATLTYINMDRS-------------LTGSP 98
            ||..|.....|||.:|     ||        |.|:.|.::.:.:.:|             |....
  Rat    20 PVWEEASKCLLFVDIPSKTVCRWDSISNRVQRVGVDAPVSSVALRQSGGYVATIGTKFCALNWED 84

  Fly    99 ELI-----PYPDWRSNTAGDCANSITTAYRIKVDECGRLWVLDTGTVGIGNTTTNPCPYAV---- 154
            :.:     ...|.::|...|.          |||..||.:.        |.......|..:
  Rat    85 QSVFILAMVDEDKKNNRFNDG----------KVDPAGRYFA--------GTMAEETAPAVLERHQ 131

  Fly   155 -NVFDLTTDTRIRRYELPGVDTNPNTFIANIAVDIGKNCDDAYAYFADELGYGLIAYSWEL 214
             :::.|..|..:::| ...||         |:..:..:.|....|:.|.|.|.:.|:.::|
  Rat   132 GSLYSLFPDHSVKKY-FDQVD---------ISNGLDWSLDHKIFYYIDSLSYTVDAFDYDL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
y	NP_476792.1	MRJP	119..405	CDD:308585	20/101 (20%)
Rgn	NP_113734.1	SGL	16..264	CDD:285626	37/191 (19%)
		NHL	166..>237	CDD:302697	6/17 (35%)
		WD40 repeat	203..239	CDD:293791
		NHL repeat	203..237	CDD:271320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3386
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900