Protein Alignment CG13375 and RRAS

DIOPT Version :10

• Sequence 1: NP_569837.2
• Gene: CG13375 / 30976
• FlyBaseID: FBgn0040370
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_006261.1
• Gene: RRAS / 6237
• HGNCID: 10447
• Length: 218
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 69/215 - (32%)
• Similarity: 108/215 - (50%)
• Gaps: 27/215 - (12%)

  Fly    43 PANARHKIVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYE 107
            |.:..||:||:|...|||:::..||:.:.|.:.|..|||:.:....|:.|:...||||||||..|
Human    25 PPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEE 89

  Fly   108 FPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQIHETKATTAVPIVVVGNKIDLLADGETER 172
            |.|||...:.:...|:||:.:.|..:|.||..:..||...|.....|:|:||||.||    |::|
Human    90 FGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADL----ESQR 150

  Fly   173 EVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQAKITYNLSPALRRRRQSLPQQIGNN 237
            :|. .:..|.........:.||||....|:.:.|::|:.          |:|:.::   |::..:
Human   151 QVP-RSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVR----------AVRKYQE---QELPPS 201

  Fly   238 GPSTPLHHHQHTQHHNSGGG 257
            .||.|         ...|||
Human   202 PPSAP---------RKKGGG 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13375	NP_569837.2	Ras_dva	49..239	CDD:206714	61/189 (32%)
RRAS	NP_006261.1	M_R_Ras_like	28..191	CDD:133345	60/177 (34%)
		Effector region	58..66		4/7 (57%)