Protein Alignment CG13375 and RHEB

DIOPT Version :10

• Sequence 1: NP_569837.2
• Gene: CG13375 / 30976
• FlyBaseID: FBgn0040370
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_005605.1
• Gene: RHEB / 6009
• HGNCID: 10011
• Length: 184
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 57/179 - (31%)
• Similarity: 89/179 - (49%)
• Gaps: 19/179 - (10%)

  Fly    43 PANARHKIVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYE 107
            |.:...||.::|...|||:|:..||:...|...|..|||.......::.|....|.::||||..|
Human     2 PQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDE 66

  Fly   108 ---FPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQIHETKATTAVPIVVVGNKIDLLADGE 169
               ||...::.|   :.:||||.||...:||.::.|..::.:......:||::||||.||    .
Human    67 YSIFPQTYSIDI---NGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDL----H 124

  Fly   170 TEREVEY----ATTESVVTVDWENGFVEASASSNENITQVFKELLAQAK 214
            .||.:.|    |..||     |...|:|:||..|:....||:.::.:|:
Human   125 MERVISYEEGKALAES-----WNAAFLESSAKENQTAVDVFRRIILEAE 168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13375	NP_569837.2	Ras_dva	49..239	CDD:206714	56/173 (32%)
RHEB	NP_005605.1	RheB	6..184	CDD:206709	56/175 (32%)
		Effector region. /evidence=ECO:0000305	35..43		4/7 (57%)