DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13375 and Ric

DIOPT Version :9

Sequence 1:	NP_001162628.1	Gene:	CG13375 / 30976	FlyBaseID:	FBgn0040370	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001163165.1	Gene:	Ric / 36776	FlyBaseID:	FBgn0265605	Length:	264	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	71/238 - (29%)
Similarity:	114/238 - (47%)	Gaps:	38/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PSFMKDDNAEDKPKRDKVGRNNAVDDAIGPANAR-----HKIVVMGSAKVGKTSIITQFLYNTFS 73
            ||..:|:.:..||            ..:.|.|.|     :|||::|...|||:::..||:.::|.
  Fly    33 PSDHRDNGSLIKP------------PPVPPQNMRGGLRVYKIVILGDGGVGKSAVTLQFVSHSFL 85

  Fly    74 TKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYEFPAMRALSISSADAFILVYDVTDATTFEEVR 138
            ..:..|||:.:|....|...:..||||||||..||.|||...:...:.||:.|.|||..:|:|..
  Fly    86 DYHDPTIEDSYQQQAVIDNEAALLDILDTAGQVEFTAMRDQYMRCGEGFIICYSVTDRHSFQEAS 150

  Fly   139 TIRDQIHETKATTAVPIVVVGNKIDLLADGETEREVEYATTESVVTVDWENG--FVEASASSNEN 201
            ..|..|...:.:..:|:|::.||:||    |::|.|   |||....:..:.|  |.|.||:....
  Fly   151 EYRKLITRVRLSEDIPLVLIANKVDL----ESQRRV---TTEEGRNLANQFGCPFFETSAALRHY 208

  Fly   202 ITQVFKELLAQAKITYNLSPALRRRRQSLPQQIGNNGPSTPLH 244
            |.:.|..|:.:.            ||:.:.:.:|.:..|..:|
  Fly   209 IDEAFYTLVREI------------RRKEMHKALGTDSNSEKIH 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13375	NP_001162628.1	RAS	48..215	CDD:214541	58/168 (35%)
CG13375	NP_001162628.1	Ras_dva	49..239	CDD:206714	61/191 (32%)
Ric	NP_001163165.1	Rit_Rin_Ric	58..229	CDD:206712	60/189 (32%)
Ric	NP_001163165.1	small_GTPase	58..223	CDD:197466	59/183 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24070
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840