DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13375 and RASD2

DIOPT Version :9

Sequence 1:	NP_001162628.1	Gene:	CG13375 / 30976	FlyBaseID:	FBgn0040370	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	XP_016884190.1	Gene:	RASD2 / 23551	HGNCID:	18229	Length:	278	Species:	Homo sapiens

Alignment Length:	192	Identity:	74/192 - (38%)
Similarity:	119/192 - (61%)	Gaps:	11/192 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PANARHKIVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYE 107
            ||...:::||:|:::|||:||:::||...|..:|..|||:.|:..::|.|....||||||:|::.
Human    27 PAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91

  Fly   108 FPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQI--------HETKATTAVPIVVVGNKIDL 164
            |||||.|||.:.|.||||:.:.:..:|:||:.::.||        ::||....:|:|:.|||.|
Human    92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKND- 155

  Fly   165 LADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQAKITYNLSPALRRR 226
              .||..|:|.....|.:|:.|....:.|.||..|.|:.::|..|.:.||:.:.:||||.|:
Human   156 --HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRK 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13375	NP_001162628.1	RAS	48..215	CDD:214541	66/174 (38%)
CG13375	NP_001162628.1	Ras_dva	49..239	CDD:206714	72/186 (39%)
RASD2	XP_016884190.1	Rhes_like	32..278	CDD:133343	72/187 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1398885at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820