DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cin and moc-2

DIOPT Version :9

Sequence 1:	NP_477030.1	Gene:	cin / 30973	FlyBaseID:	FBgn0000316	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001370857.1	Gene:	moc-2 / 189078	WormBaseID:	WBGene00003385	Length:	168	Species:	Caenorhabditis elegans

Alignment Length:	174	Identity:	78/174 - (44%)
Similarity:	104/174 - (59%)	Gaps:	20/174 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VLTISDTCWQEPEKDTSGPILRQLIGETFANTQVIGN-----IVPDEKDIIQQ---ELRKWIDRE 64
            |:|:||||......|.|||.|.:|: :|.|......|     :|||:...|..   |..|:.|
Worm     5 VITVSDTCSAGTRTDESGPKLVELV-DTSAVVNATVNEGSPFVVPDDVTAIHDALVEQSKFAD-- 66

  Fly    65 ELRVILTTGGTGFAPRDVTPEATRQLLEKECPQLSMYITLESIKQTQYAALSRGLCGIAGNTLIL 129
               ||||||||||||||||||||.:::::.|..|.:.:...|:|.|..|||||.:.||.|.|||:
Worm    67 ---VILTTGGTGFAPRDVTPEATLKVIDRRCSGLEIALHTASLKITSMAALSRAIVGIRGGTLIV 128

  Fly   130 NLPGSEKAVKECFQTISALLPHAVHLI--GDDVSLVRKTHAEVQ 171
            |:|||.||||||:.|:..||.|.::|:  .||.|    .||.::
Worm   129 NMPGSVKAVKECWDTLEPLLNHGINLLKNTDDGS----QHARMK 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cin	NP_477030.1	MogA_MoaB	4..156	CDD:238451	72/155 (46%)
		MoeA	198..595	CDD:223380
		MoeA	211..592	CDD:238452
moc-2	NP_001370857.1	MogA_MoaB	1..155	CDD:238451	72/155 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I3649
eggNOG	1	0.900	-	-		E1_COG0303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5710
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3940
SonicParanoid	1	1.000	-	-		X2231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.790