Protein Alignment cin and gphn

DIOPT Version :9

• Sequence 1: NP_477030.1
• Gene: cin / 30973
• FlyBaseID: FBgn0000316
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_017951593.2
• Gene: gphn / 100124966
• XenbaseID: XB-GENE-989642
• Length: 970
• Species: Xenopus tropicalis
• Alignment Length: 936
• Identity: 252/936 - (26%)
• Similarity: 366/936 - (39%)
• Gaps: 365/936 - (38%)

  Fly     4 ITFGVLTISDTCWQEPEKDTSGPILRQLIGE--TFANTQVIGNIVPDEKDIIQQELRKWIDREEL 66
            |..||||:||:|::...:|.||..|:.|:.:  ....|.....|||||.|.|::.|..|.|.:||
 Frog    50 IRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIDDIKESLIDWCDEKEL 114

  Fly    67 RVILTTGGTGFAPRDVTPEATRQLLEKECPQLSMYITLESIKQTQYAALSRGLCGIAGNTLILNL 131
            .:||||||||||||||||||||:::|:|.|.:::.:.:.|:..|....|||.:|||.|.|||:||
 Frog   115 NLILTTGGTGFAPRDVTPEATREVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINL 179

  Fly   132 PGSEKAVKECFQTISALLPHAVHLIGDDVSLVRKTHAEVQG------------------------ 172
            |||:|..:||||.|...||||:.|:.|.:..|::.|.|::.
 Frog   180 PGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKG 244

  Fly   173 -------------------SAQKSHI--------------------------------------- 179
                               .:..|||
 Frog   245 VQCEEEEEEKKDSGVASTEDSSSSHITAATIAAKSSIAAIMAKGQASIPGVISHHPTANAVEPGF 309

  Fly   180 ---CPHKTGTGTDSDRNSPYPML------------------------------------------ 199
               |.|.|.:      ::|.|.:
 Frog   310 ISCCHHHTSS------SAPEPTVSSSSHHLSSSTVKPTLISSSHHTTSSSLEPSHSSCSHHASSS 368

  Fly   200 -------------------PVQEVLSIIFNTVQ----KTANL----------------------- 218
                               |:.:  |||...||    .||:|
 Frog   369 SVEAVPTSCSHHTTSTALEPIPD--SIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPT 431

  Fly   219 ---------NKIL----------------------------LEMNA------------------- 227
                     ||::                            |.:||
 Frog   432 PKQIRRPDENKVITNRVGSFKLHRKLENLRDHLQGNDKGYSLRVNARLPSCSSTYSVSEDIWIAA 496

  Fly   228 ----------------------------------------------------------------- 227
                                                                             
 Frog   497 PSFSQLHYKLEGLKDELRRNRGCETRVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMD 561

  Fly   228 ----------PV------------------------NIPPFRASIKDGYAMKSTGFSGTKRVLGC 258
                      ||                        |:|||.||:|||||:::....|.:.::|.
 Frog   562 KAFITVLEMTPVLGTEIINYRDGMGRVLAQEVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGE 626

  Fly   259 IAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQLDKNGQESL-VDILVEPQAGLD 322
            ..||:.|.. .:...:..::.||||:|..||.|||||||:|::...:|.|.| |.|||:.:.|.|
 Frog   627 SQAGEQPTQ-TVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQD 690

  Fly   323 VRPVGYDLSTNDRIFPA---LDPSPVVVKSLLASVG-NRLILSK-PKVAIVSTGSELCSPRNQLT 382
            :||:|:|:...:.:...   :.||.:   .|||:|| ..:.:.| |.||::|||:||.:|.:.|.
 Frog   691 IRPIGHDIKRGECVLAKGTHMGPSEI---GLLATVGVTEVEVHKFPVVAVMSTGNELLNPEDDLL 752

  Fly   383 PGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTKESLLELFEVVDFVICSGGVSMGDKDFVK 447
            ||||.|||.:.|...:...|:..::..::.|:......:|.|.....|.:|.|||||||:||::|
 Frog   753 PGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLK 817

  Fly   448 SVLE-DLQFRIHCGRVNIKPGKPMTFASRK----DKYFFGLPGNPVSAFVTFHLFALPAIRFAAG 507
            .||: ||..:||.|||.:|||.|.|||:..    .|..|.||||||||.||.:||.:||:|...|
 Frog   818 QVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQG 882

  Fly   508 WDRCKCSL----SVLNVKLLNDFSLDSRPEFVRASVISKSGE--LYASVNGNQISSRLQSIVGAD 566
                  .|    :::..:|..|..||.|||:.|..:.....|  .:|...|||:||||.|:..|:
 Frog   883 ------ILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSAN 941

  Fly   567 VLINLPARTSDRPLAKAGEIFPASVL 592
            .|:.||.:|........||:....|:
 Frog   942 GLLMLPPKTEQYVELHKGEVVDVMVI 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cin	NP_477030.1	MogA_MoaB	4..156	CDD:238451	76/153 (50%)
		MoeA	198..595	CDD:223380	163/655 (25%)
		MoeA	211..592	CDD:238452	158/579 (27%)
gphn	XP_017951593.2	MogA_MoaB	50..204	CDD:238451	76/153 (50%)
		MoeA	561..967	CDD:238452	148/415 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4654
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H10820
Inparanoid	1	1.050	386	1.000	Inparanoid score	I1980
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1114121at2759
OrthoFinder	1	1.000	-	-		FOG0003343
OrthoInspector	1	1.000	-	-		oto103148
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3940
SonicParanoid	1	1.000	-	-		X2231
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090