Protein Alignment G9a and SUV39H2

DIOPT Version :10

• Sequence 1: NP_001259088.1
• Gene: G9a / 30971
• FlyBaseID: FBgn0040372
• Length: 1657
• Species: Drosophila melanogaster
• Sequence 2: NP_001180353.1
• Gene: SUV39H2 / 79723
• HGNCID: 17287
• Length: 410
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 85/229 - (37%)
• Similarity: 118/229 - (51%)
• Gaps: 39/229 - (17%)

  Fly  1418 CSCLDSCSSDRCQCNGASSQNWYTAESRLNADFNYED-----PAV-IFECNDVCGCNQLSCKNRV 1476
            |||.| |...:| |         .||:.:...:|...     |.. |:|||..|.|.. .|.||:
Human   191 CSCTD-CFFQKC-C---------PAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGP-DCPNRI 243

  Fly  1477 VQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRR---TDD---SYYFD 1535
            ||.||:..|.|....: .:||||:.|..:.:.:||..|.||::|:.||:||   .|:   :|.||
Human   244 VQKGTQYSLCIFRTSN-GRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFD 307

  Fly  1536 LD---NGHCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDY 1597
            ||   :...:||..||||:.|.||||:||:....||.::.|.|.|:||.||.|.|:||||:.|||
Human   308 LDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDY 372

  Fly  1598 GEK------FWRVEH-----RSCVGCRCLTTTCK 1620
            ..|      ...::|     |....|:|...||:
Human   373 QMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCR 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	PTZ00121	<68..>188	CDD:173412
		EHMT_ZBD	786..933	CDD:411018
		ANKYR	1063..1322	CDD:440430
		ANK repeat	1088..1120	CDD:293786
		ANK repeat	1124..1153	CDD:293786
		ANK repeat	1155..1196	CDD:293786
		ANK repeat	1199..1249	CDD:293786
		ANK repeat	1251..1283	CDD:293786
		ANK repeat	1285..1316	CDD:293786
		SET_EHMT	1391..1622	CDD:380941	85/229 (37%)
SUV39H2	NP_001180353.1	CD_SUV39H1_like	47..95	CDD:349289
		SET_SUV39H2	167..409	CDD:380930	85/229 (37%)