DRSC/TRiP Functional Genomics Resources

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Protein Alignment G9a and setdb1b

DIOPT Version :10

Sequence 1:NP_001259088.1 Gene:G9a / 30971 FlyBaseID:FBgn0040372 Length:1657 Species:Drosophila melanogaster
Sequence 2:XP_005158070.3 Gene:setdb1b / 768131 ZFINID:ZDB-GENE-061013-224 Length:1242 Species:Danio rerio


Alignment Length:548 Identity:102/548 - (18%)
Similarity:150/548 - (27%) Gaps:287/548 - (52%)


- Green bases have known domain annotations that are detailed below.


  Fly  1344 RSFRPLGLRTFVVCADASNGREARPIQVVRNELAMSENEDEADSLMWPDFRYVTQCIIQQNSVQI 1408
            |.|:|  .|.|....|.::|||..|:..|          :|.|:...|...|..: .|.::.|.|
Zfish   707 RRFQP--QRPFYFIRDITSGREDIPLSCV----------NEIDNTPPPSVAYSKE-RIPEDGVYI 758

  Fly  1409 DRRVSQMRICSCLDSC-SSDRCQCNGASSQ-NWYTAESRL--NADFNYED-----PAVIFECNDV 1464
            :.....:..|.|.|.| ...:|.|:..:.| ...|...::  ||.::|:.     |..|:|||..
Zfish   759 NTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKR 823

  Fly  1465 CGCNQLSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADR--- 1526
            |.||...|.||:||:|.:..||:.  :.|.||||:|.|.::.||:||..|.|:|||...||:   
Zfish   824 CRCNMQMCTNRLVQHGLQVRLQLF--KTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGL 886

  Fly  1527 RTDDSYYFDLDN--------------GHC------------------------------------ 1541
            ...|.|:.:||:              .||                                    
Zfish   887 EMGDEYFANLDHIESVENFKEGYESEAHCSDSEGSGVDMSRVKLPASSRHGKSNKMEERNSSTTG 951

  Fly  1542 ----------------------------------------------------------------- 1541
                                                                             
Zfish   952 KSQDDSSEESDDEKDDDSNEDDSDSSDDTFVKDTYYTTSSVWRSYTTRRQAKGLKEESQDSKDGM 1016

  Fly  1542 ----------------------------------------------------------------- 1541
                                                                             
Zfish  1017 SVSAGEDRKPPHMPEETGKSKVASWLTNQSSTSANQSLKVEGGIKTEKKDVMTLSDSDDVQTISS 1081

  Fly  1542 ----------------------------------------------------------------- 1541
                                                                             
Zfish  1082 GSDDNKEREKKTQAVVKRQVAVKSTRGIALKSHSMMVKSGGGGAGGGGSGPSHGHGGGGGDNGPK 1146

  Fly  1542 --------------IDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEE 1592
                          |||...||:.|:.||||.||:....||.:..|.|||.:|||:.:.|.||.|
Zfish  1147 NTRLFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE 1211

  Fly  1593 ICFDYGEKFWRVEHRSCVGCRCLTTTCK 1620
            :.:||..:...||.:..: |.|.:|.|:
Zfish  1212 LTWDYNYEVGSVEGKELL-CCCGSTECR 1238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
G9aNP_001259088.1 PTZ00121 <68..>188 CDD:173412
EHMT_ZBD 786..933 CDD:411018
ANKYR 1063..1322 CDD:440430
ANK repeat 1088..1120 CDD:293786
ANK repeat 1124..1153 CDD:293786
ANK repeat 1155..1196 CDD:293786
ANK repeat 1199..1249 CDD:293786
ANK repeat 1251..1283 CDD:293786
ANK repeat 1285..1316 CDD:293786
SET_EHMT 1391..1622 CDD:380941 89/501 (18%)
setdb1bXP_005158070.3 None
Blue background indicates that the domain is not in the aligned region.

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