Protein Alignment G9a and LOC4577143

DIOPT Version :10

• Sequence 1: NP_001259088.1
• Gene: G9a / 30971
• FlyBaseID: FBgn0040372
• Length: 1657
• Species: Drosophila melanogaster
• Sequence 2: XP_313355.5
• Gene: LOC4577143 / 4577143
• VectorBaseID: AGAMI1_013464
• Length: 851
• Species: Anopheles gambiae
• Alignment Length: 836
• Identity: 191/836 - (22%)
• Similarity: 290/836 - (34%)
• Gaps: 291/836 - (34%)

  Fly   834 LRPSQRVSYMILCDEHKKRLQSHNCCAGCGIFCTQGKFVLCKQQHFFHPD-CAQRFILSTSYEKE 897
            :.|.:|::...| ...::|.:..:|.|      .||.|   ...|...|: ..:|...|....|:
Mosquito   164 MSPPERITQPSL-HASRERARRKSCPA------AQGNF---SGTHIPKPNGFPKRMSCSIDKVKK 218

  Fly   898 LGDEEDQGVKFSSPVLVLKCPHCGLDTPERTSTVTMKCQSLPVFLRTQKYKIK-------PARLT 955
            ..||.:.|.:|..|            |..|.:|:..: |:.|     .|..||       |..::
Mosquito   219 EVDESEDGSRFDVP------------TDTRLATINQE-QATP-----DKQNIKVECSDETPDAMS 265

  Fly   956 TSSHLTQFGTVEN-ANTPGATARNK--GGLSTAVT------------LSAASSPASKT------- 998
            :||.      ||| ..||..||..|  .|..|.||            :.:|:.|:.||
Mosquito   266 SSSQ------VENGTETPKTTASVKVENGTDTPVTPVARDNSNGLLKVMSAAKPSPKTSTPKTTA 324

  Fly   999 -----NGAQRGRAGTSNSNSRHALNSINFAQLIPESVMNVVLRGHVVSASGRVTAEFTPRDMYYA 1058
                 ||........|..:|:..||.                         ::.|:.:|:.....
Mosquito   325 SIKVENGTVSPATPVSRDSSKGLLNV-------------------------KLAAKPSPKTPATG 364

  Fly  1059 VQNDDLERVAEILAADFNVLTPIREYL-NGTCLHLVAHSGTLQMAYLL-----LCKGASSPDF-V 1116
            .:|..|..         ...||.|:.. .|:....:..|.|....|.:     :....:||.| |
Mosquito   365 ERNSSLSA---------GKSTPKRKSTGGGSNSKQIKKSATTSKEYTVENIEDIQLVGNSPFFLV 420

  Fly  1117 NIVDYELRTALMCAVMN-EKCDMLNLFLQCGADVAIKGPDGKTSLHIAAQLGNLEA-TQLIVDSY 1179
            ..:.|..:......:.| ..|.||:.||                   :||:..||. .:.:.:..
Mosquito   421 KWLGYTSKDNTWEPLNNVNSCAMLDSFL-------------------SAQMSLLEEWVEPLQEKI 466

  Fly  1180 RTSRNITSFLSFIDAQ------------DEGGWTAMVWAAELGHTDIVRLASLPQAVFLKLINIF 1232
            |:|   ..:|..::.|            .|..|..:       ..|::.:|.|..
Mosquito   467 RSS---PEYLESLERQGSKTYQEILLEHKEYDWDQL-------RADLIIMAKLWM---------- 511

  Fly  1233 LFISFLLNQDADPNICDNDNNTVLHWSTLHNDGLDTITVLLQSGADCNVQNVEGDTPLHIACRHS 1297
                             |.....|.|        :.||.|:                    ||
Mosquito   512 -----------------NRGRNKLIW--------ERITRLM--------------------CR-- 529

  Fly  1298 VTRMCIALIANGADLMIKNKAEQLPFDCIPNEESECGRTVGFNMQMRSFRPLGLRTFVVCADASN 1362
                         :|....:.|||         .|..|   |...:....|. ||..|
Mosquito   530 -------------ELSYAKRCEQL---------EELRR---FEKHINDHEPT-LRVVV------- 561

  Fly  1363 GREARPIQVVRNELAMSENEDEADSLMWP--DFRYVTQCIIQQN-SVQIDRRVSQMRICSCLDSC 1424
                             |||.:.|:   |  :|.|:...|..:. |:..|..|.    |.| :.|
Mosquito   562 -----------------ENEHDLDA---PPNNFTYLQGNIPAEGISIPNDPPVG----CEC-NPC 601

  Fly  1425 SSDRCQCNGASSQN--WYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQI 1487
            :. |..|.|..|:.  .|:.:.||    ..:..|.|||||..|.|.. .|.|||||||.:..|.:
Mosquito   602 TG-RSTCCGKLSEGRFAYSVKKRL----LLQPGAPIFECNKKCSCGP-DCLNRVVQNGGKCNLTL 660

  Fly  1488 VECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRRTDD------SYYFDL-----DNGHC 1541
            .:..: .:|||||....:.:|.::..|.||:::..||::|..:      :|.|||     ||.:.
Mosquito   661 FKTPN-GRGWGVRTNTVIYEGQYISEYCGEVISYDEAEKRGREYDAVGRTYLFDLDFNGTDNPYT 724

  Fly  1542 IDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDY 1597
            :||..||||||||||||:||.....|:.:..|...|::|||:.|.|:.|||:.|:|
Mosquito   725 LDAARYGNVTRFFNHSCDPNCGIWSVWIDCLDPYLPRLAFFAQRRIEIGEELTFNY 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	PTZ00121	<68..>188	CDD:173412
		EHMT_ZBD	786..933	CDD:411018	22/99 (22%)
		ANKYR	1063..1322	CDD:440430	43/279 (15%)
		ANK repeat	1088..1120	CDD:293786	7/37 (19%)
		ANK repeat	1124..1153	CDD:293786	6/29 (21%)
		ANK repeat	1155..1196	CDD:293786	8/53 (15%)
		ANK repeat	1199..1249	CDD:293786	4/49 (8%)
		ANK repeat	1251..1283	CDD:293786	5/31 (16%)
		ANK repeat	1285..1316	CDD:293786	3/30 (10%)
		SET_EHMT	1391..1622	CDD:380941	81/223 (36%)
LOC4577143	XP_313355.5	None