Protein Alignment G9a and E(z)

DIOPT Version :10

• Sequence 1: NP_001259088.1
• Gene: G9a / 30971
• FlyBaseID: FBgn0040372
• Length: 1657
• Species: Drosophila melanogaster
• Sequence 2: NP_001261682.1
• Gene: E(z) / 39203
• FlyBaseID: FBgn0000629
• Length: 765
• Species: Drosophila melanogaster
• Alignment Length: 230
• Identity: 71/230 - (30%)
• Similarity: 95/230 - (41%)
• Gaps: 45/230 - (19%)

  Fly  1399 CIIQQNSVQIDRRVSQMRICSCLDSCSSD----RC--QCNGASSQNWYTAESRLNADFNYEDPAV 1457
            ||..||..:        :.|:|...|.:.    ||  ||| ......|.|....:.|.
  Fly   556 CIQTQNFCE--------KFCNCSSDCQNRFPGCRCKAQCN-TKQCPCYLAVRECDPDL------- 604

  Fly  1458 IFECNDVCGCNQ-----LSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGE 1517
               | ..||.:|     ::|||..||.|....|.:...:  ..|||:.......|..|:..|.||
  Fly   605 ---C-QACGADQFKLTKITCKNVCVQRGLHKHLLMAPSD--IAGWGIFLKEGAQKNEFISEYCGE 663

  Fly  1518 ILTAMEADRRTD------DSYYFDLDNGHCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRF 1576
            |::..|||||..      .|:.|:|:|...:||...||..||.|||..||.. .:|.....|:|
  Fly   664 IISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINPNCY-AKVMMVTGDHR- 726

  Fly  1577 PKIAFFSCRDIDAGEEICFDYGEKFWRVEHRSCVG 1611
              |..|:.|.|..|||:.|||  ::...|....||
  Fly   727 --IGIFAKRAIQPGEELFFDY--RYGPTEQLKFVG 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	PTZ00121	<68..>188	CDD:173412
		EHMT_ZBD	786..933	CDD:411018
		ANKYR	1063..1322	CDD:440430
		ANK repeat	1088..1120	CDD:293786
		ANK repeat	1124..1153	CDD:293786
		ANK repeat	1155..1196	CDD:293786
		ANK repeat	1199..1249	CDD:293786
		ANK repeat	1251..1283	CDD:293786
		ANK repeat	1285..1316	CDD:293786
		SET_EHMT	1391..1622	CDD:380941	71/230 (31%)
E(z)	NP_001261682.1	PRC2_HTH_1	151..291	CDD:436286
		SANT	452..492	CDD:238096
		preSET_CXC	579..610	CDD:408079	10/42 (24%)
		SET_EZH2	628..747	CDD:380995	44/126 (35%)