DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment G9a and Suv39h1l1

DIOPT Version :9

Sequence 1:	NP_001259088.1	Gene:	G9a / 30971	FlyBaseID:	FBgn0040372	Length:	1657	Species:	Drosophila melanogaster
Sequence 2:	NP_001100426.1	Gene:	Suv39h1l1 / 302553	RGDID:	1565028	Length:	413	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	101/302 - (33%)
Similarity:	137/302 - (45%)	Gaps:	68/302 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1364 REARPIQVVRNELAMSENEDEADSLMWP--DFRYVTQCIIQQ----NSVQIDRRVSQMRICSCLD 1422
            |..:.:...|:.|.....|:|.| |..|  .|.|:.:..:.:    |.|.:.        |.|.|
  Rat   131 RWEQELNAKRSHLGRITVENEVD-LDGPPRSFVYINEYRVGEGITLNQVAVG--------CECQD 186

  Fly  1423 S--CSSDRCQCNGASSQNWYTAESRLNADFNYEDPA--------VIFECNDVCGCNQLSCKNRVV 1477
            .  ..:..| |.|||...           |.|.|..        .|:|||..|.|. ..|.||||
  Rat   187 CLLAPTGGC-CPGASLHK-----------FAYNDQGQVRLKAGQPIYECNSRCCCG-YDCPNRVV 238

  Fly  1478 QNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADR------RTDDSYYFDL 1536
            |.|.|..|.|...:| .:|||||.|..:.|.:||..|.|||:|:.||:|      |...:|.|||
  Rat   239 QKGIRYNLCIFRTDD-GRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDL 302

  Fly  1537 D---NGHCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYG 1598
            |   :.:.:||.||||::.|.||||:||:....||.::.|.|.|:||||:.|.|.||||:.|||.
  Rat   303 DYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYN 367

  Fly  1599 EKFWRVEHRSC--------------------VGCRCLTTTCK 1620
            .:...|:..|.                    :.|:|.||.|:
  Rat   368 MQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTTACR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	ATP-synt_B	150..248	CDD:304375
		Ank_2	1056..1152	CDD:289560
		ANK	1088..1217	CDD:238125
		ANK repeat	1088..1120	CDD:293786
		ANK repeat	1124..1153	CDD:293786
		Ank_2	1127..1249	CDD:289560
		ANK	1155..1306	CDD:238125
		ANK repeat	1155..1196	CDD:293786
		ANK repeat	1199..1249	CDD:293786
		Ank_2	1205..1316	CDD:289560
		ANK repeat	1251..1283	CDD:293786
		ANK repeat	1285..1316	CDD:293786
		PreSET	1357..1466	CDD:128744	27/117 (23%)
		SET	1495..1602	CDD:214614	54/115 (47%)
Suv39h1l1	NP_001100426.1	Chromo	45..92	CDD:278797
		PreSET	133..228	CDD:128744	26/115 (23%)
		SET	244..367	CDD:214614	56/123 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D753093at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820