Protein Alignment G9a and set-11

DIOPT Version :10

• Sequence 1: NP_001259088.1
• Gene: G9a / 30971
• FlyBaseID: FBgn0040372
• Length: 1657
• Species: Drosophila melanogaster
• Sequence 2: NP_001364763.1
• Gene: set-11 / 185242
• WormBaseID: WBGene00018023
• Length: 278
• Species: Caenorhabditis elegans
• Alignment Length: 281
• Identity: 91/281 - (32%)
• Similarity: 131/281 - (46%)
• Gaps: 43/281 - (15%)

  Fly  1355 VVCADASNGREARPIQVVRNELAMSENEDEADSLMWPDFRYVTQCIIQQNSVQIDRRVSQMRICS 1419
            |:..|.|.|.|...:.|..|....      .||.::.:|:| |..||........|..|...:|.
 Worm    19 VLYEDISQGCERFVVPVYSNPRFF------MDSSLFENFKY-TSRIIDVAGQLACRSASPTFMCQ 76

  Fly  1420 CLDSCSSDRCQCN------GASSQN-----WYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCK 1473
            |...||:: |:|:      |.:.:|     |.|                :.|||:.|.| .|.|.
 Worm    77 CAGQCSTN-CECSSGVFGEGGTVENMELLMWDT----------------VRECNEYCNC-ALWCG 123

  Fly  1474 NRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRRTDDSYYFDLDN 1538
            |||.|.|...|::|. ..|...||||||..::..|||:|.|.||::...||..|.|.::.|:...
 Worm   124 NRVAQKGAMYPVEIF-ARDPWCGWGVRASVDIAFGTFIGEYAGELIDDEEAMDRHDSTFLFETKV 187

  Fly  1539 GH---CIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYGEK 1600
            |.   .|||.|.||.|||.||||.|||....:.:::...:...:.||:.:.|..|||:..||||.
 Worm   188 GSETLTIDAKYSGNYTRFINHSCAPNVKVANISWDYDKIQLIHMCFFTDKAIRKGEELTIDYGEA 252

  Fly  1601 FWRVEHRSCVGCRCLTTTCKY 1621
            :|..:...|:   |.::.|:|
 Worm   253 WWANKKFPCL---CKSSECRY 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	PTZ00121	<68..>188	CDD:173412
		EHMT_ZBD	786..933	CDD:411018
		ANKYR	1063..1322	CDD:440430
		ANK repeat	1088..1120	CDD:293786
		ANK repeat	1124..1153	CDD:293786
		ANK repeat	1155..1196	CDD:293786
		ANK repeat	1199..1249	CDD:293786
		ANK repeat	1251..1283	CDD:293786
		ANK repeat	1285..1316	CDD:293786
		SET_EHMT	1391..1622	CDD:380941	82/245 (33%)
set-11	NP_001364763.1	PreSET	21..117	CDD:128744	28/119 (24%)
		SET	75..270	CDD:394802	74/216 (34%)