DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment G9a and met-1

DIOPT Version :9

Sequence 1:	NP_001259088.1	Gene:	G9a / 30971	FlyBaseID:	FBgn0040372	Length:	1657	Species:	Drosophila melanogaster
Sequence 2:	NP_491340.2	Gene:	met-1 / 172026	WormBaseID:	WBGene00016603	Length:	1604	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	77/283 - (27%)
Similarity:	123/283 - (43%)	Gaps:	68/283 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1365 EARPIQVVRNELAMSENEDEA-----------DSLMWPDFRYVTQC-IIQQNSVQIDRRVSQMRI 1417
            |...||...:|  ..:.||||           :.:..|:|..:::. .:.:|:   :::.::...
Worm   581 EEERIQKENDE--KKQKEDEAKMEEEKKKIKEEEMKIPEFELISESKYLTRNA---NKKKTESLT 640

  Fly  1418 CSCL---DSCSSDRCQCNGASSQNWYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQN 1479
            |.|.   .:||.:.|                       .:.|::.||...|   |:.|||   |.
Worm   641 CECHRTGGNCSDNTC-----------------------VNRAMLTECPSSC---QVKCKN---QR 676

  Fly  1480 GTRTPLQIVEC--EDQAKGWGVRALANVPKGTFVGSYTGEIL---------TAMEADRRTDDSYY 1533
            ..:.....||.  ...|||.|:||:.::.||.|:..|.||::         |...||::  ..::
Worm   677 FAKKKYAAVEAFHTGTAKGCGLRAVKDIKKGRFIIEYIGEVVERDDYEKRKTKYAADKK--HKHH 739

  Fly  1534 FDLDNG-HCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDY 1597
            :..|.| :.|||..|||.:||.||||:||.:..:...........::.|||.|.|.|||||.|||
Worm   740 YLCDTGVYTIDATVYGNPSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDY 804

  Fly  1598 GEKFWRVEH-RSCVGCRCLTTTC 1619
              :|  |.: |....|.|.:.:|
Worm   805 --QF--VNYGRDAQQCFCGSASC 823

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	ATP-synt_B	150..248	CDD:304375
		Ank_2	1056..1152	CDD:289560
		ANK	1088..1217	CDD:238125
		ANK repeat	1088..1120	CDD:293786
		ANK repeat	1124..1153	CDD:293786
		Ank_2	1127..1249	CDD:289560
		ANK	1155..1306	CDD:238125
		ANK repeat	1155..1196	CDD:293786
		ANK repeat	1199..1249	CDD:293786
		Ank_2	1205..1316	CDD:289560
		ANK repeat	1251..1283	CDD:293786
		ANK repeat	1285..1316	CDD:293786
		PreSET	1357..1466	CDD:128744	19/115 (17%)
		SET	1495..1602	CDD:214614	43/116 (37%)
met-1	NP_491340.2	PHA03283	<219..308	CDD:223032
		AWS	637..682	CDD:197795	14/73 (19%)
		SET	694..810	CDD:214614	45/121 (37%)
		tolA_full	<1300..>1375	CDD:274303
		WW	1366..1393	CDD:238122
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165870
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D753093at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850