DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment G9a and setmar

DIOPT Version :9

Sequence 1:	NP_001259088.1	Gene:	G9a / 30971	FlyBaseID:	FBgn0040372	Length:	1657	Species:	Drosophila melanogaster
Sequence 2:	NP_001107735.1	Gene:	setmar / 100135741	XenbaseID:	XB-GENE-490240	Length:	284	Species:	Xenopus tropicalis

Alignment Length:	269	Identity:	84/269 - (31%)
Similarity:	115/269 - (42%)	Gaps:	70/269 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1391 PDFRYVTQCIIQQNSVQIDRRVSQMRICSCLDS-CSSDRCQCNGASSQNWYTAESRLNADFNYED 1454
            |.|:|..:.|....:.|....|: ::.|.|..| |.::.|.|              |....||..
Frog    35 PAFQYTPELIAGPGAEQDPSEVT-IQGCDCRGSNCVAELCSC--------------LPHGTNYVR 84

  Fly  1455 PAVIF------ECNDVCGCNQLSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGS 1513
            ..::.      ||:.:|.|.: ||.||..|.|.:..||:  |:...|||||..|.::|.|.||..
Frog    85 RTIVSGQRPVRECHIMCSCGE-SCPNRETQQGLQYQLQL--CQRPGKGWGVCTLEDIPSGRFVCE 146

  Fly  1514 YTGEILTAMEADRRTDDSYYFDLDNGHC---------------------IDANYYGNVTRFFNHS 1557
            |.||:|...:|..||       |....|                     :|..:.|||.||.|||
Frog   147 YAGEVLGHEQARSRT-------LSQNPCANNYIIAVREHLHGGQILQTFVDPTHIGNVGRFLNHS 204

  Fly  1558 CEPN--VLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYGEKFWR----------VEHRSCV 1610
            |:||  ::|||.   |.  ..||:|.|:.|||.||||:|:||..||:.          .|..|..
Frog   205 CDPNLFMMPVRT---HS--MVPKLALFAARDIQAGEELCYDYSGKFFNQTPACETLDPEEPSSRK 264

  Fly  1611 GCRCLTTTC 1619
            .|:|....|
Frog   265 KCQCGARAC 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
G9a	NP_001259088.1	ATP-synt_B	150..248	CDD:304375
		Ank_2	1056..1152	CDD:289560
		ANK	1088..1217	CDD:238125
		ANK repeat	1088..1120	CDD:293786
		ANK repeat	1124..1153	CDD:293786
		Ank_2	1127..1249	CDD:289560
		ANK	1155..1306	CDD:238125
		ANK repeat	1155..1196	CDD:293786
		ANK repeat	1199..1249	CDD:293786
		Ank_2	1205..1316	CDD:289560
		ANK repeat	1251..1283	CDD:293786
		ANK repeat	1285..1316	CDD:293786
		PreSET	1357..1466	CDD:128744	17/81 (21%)
		SET	1495..1602	CDD:214614	50/129 (39%)
setmar	NP_001107735.1	SET_SETMAR	35..282	CDD:380942	84/269 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D563968at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920